Ewing's Sarcoma/Primitive Neuroectodermal Tumor of the Kidney

被引：12

作者：

Funahashi, Y. ^{[1
]}

Hattori, R. ^{[1
]}

Yamamoto, T. ^{[1
]}

Mizutani, K. ^{[1
]}

Yoshino, Y. ^{[1
]}

Matsukawa, Y. ^{[1
]}

Sassa, N. ^{[1
]}

Okumura, K. ^{[1
]}

Gotoh, M. ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Med, Dept Urol, Showa Ku, Nagoya, Aichi 4668550, Japan

来源：

AKTUELLE UROLOGIE | 2009年 / 40卷 / 04期

关键词：

Ewing's sarcoma; PNET; kidney; chemotherapy; immunohistochemistry; SARCOMA; FAMILY;

D O I：

10.1055/s-0028-1098827

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 42-year-old female presented with right back pain. The CT scan revealed a 72-mm space-occupying lesion in the middle portion of the right kidney. No metastasis was proven. She Underwent laparoscopic radical nephrectomy and lymph node disection. The histopathological examination revealed a high-grade primitive small round tumor the cells of which were strongly positive for CD99 and vimentin. Fluorescence in situ hybridization analysis using a DNA probe for the Ewing sarcoma breakpoint region 1 (EWSR1) on chromosome 22g12 revealed a rearrangement of the EWSR1 locus. The diagnosis was Ewing's sarcoma/primitive neuroectodermal tumor of the kidney. She underwent 13 cycles of chemotherapy, and has no evidence of recurrence 19 months after Surgery.

引用

页码：247 / 249

页数：3

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