In vitro maturation and fertilization of oocytes from an intact ovary of a surgically treated patient with endometrial carcinoma:: Case report

被引：19

作者：

Revel, A ^{[1
]}

Safran, A ^{[1
]}

Benshushan, A ^{[1
]}

Shushan, A ^{[1
]}

Laufer, N ^{[1
]}

Simon, A ^{[1
]}

机构：

[1] Hadassah Univ Hosp, Dept Obstet & Gynecol, In Vitro Fertilizat Unit, IL-91120 Jerusalem, Israel

来源：

HUMAN REPRODUCTION | 2004年 / 19卷 / 07期

关键词：

embryo cryopreservation; endometrial carcinoma; fertility preservation; in vitro maturation; polycystic ovary syndrome;

D O I：

10.1093/humrep/deh241

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Polycystic ovary syndrome (PCOS) with prolonged anovulation had resulted in endometrial carcinoma in a 43-year-old woman. Since she and her husband did not share common biological children, they requested fertility preservation. Due to the woman's age, high dose progesterone and postponing surgery were both considered inappropriate. We therefore proposed oocyte retrieval from the ovaries removed by staging laparotomy followed by in vitro maturation and ICSI. Surrogacy could then enable a future pregnancy. Fourteen of 17 (82%) retrieved oocytes matured in vitro. Following ICSI, eight embryos (two at the pronuclear stage and six cleaved) were cryopreserved. To the best of our knowledge, this is the first report of oocyte aspiration, maturation and fertilization from an ovary removed by laparotomy.

引用

页码：1608 / 1611

页数：4

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