3D Printed Microtransporters: Compound Micromachines for Spatiotemporally Controlled Delivery of Therapeutic Agents

被引：200

作者：

Huang, Tian-Yun ^{[1
,2
]}

Sakar, Mahmut Selman ^{[1
]}

Mao, Angelo ^{[3
]}

Petruska, Andrew J. ^{[1
]}

Qiu, Famin ^{[1
]}

Chen, Xue-Bo ^{[2
]}

Kennedy, Stephen ^{[4
]}

Mooney, David ^{[3
]}

Nelson, Bradley J. ^{[1
]}

机构：

[1] ETH, Inst Robot & Intelligent Syst, CH-8092 Zurich, Switzerland

[2] Liaoning Univ Sci & Technol, Sch Elect & Informat Engn, Anshan 114051, Peoples R China

[3] Harvard Univ, Sch Engn & Appl Sci, Wyss Inst Biol Inspired Engn, Cambridge, MA 02318 USA

[4] Univ Rhode Isl, Dept Elect Comp & Biomed Engn, Dept Chem Engn, Kingston, RI 02881 USA

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 42期

基金：

瑞士国家科学基金会; 欧洲研究理事会; 美国国家科学基金会; 美国国家卫生研究院; 中国国家自然科学基金;

关键词：

BIOMEDICAL APPLICATIONS; FABRICATION; DRIVEN;

D O I：

10.1002/adma.201503095

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Functional compound micromachines are fabricated by a design methodology using 3D direct laser writing and selective physical vapor deposition of magnetic materials. Microtransporters with a wirelessly controlled Archimedes screw pumping mechanism are engineered. Spatiotemporally controlled collection, transport, and delivery of micro particles, as well as magnetic nanohelices inside microfluidic channels are demonstrated.

引用

页码：6644 / +

页数：8

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