PREPARATION AND CHARACTERIZATION OF THE INCLUSION COMPLEX ESSENTIAL OIL OF Croton zehntneri WITH β-CYCLODEXTRIN

被引：24

作者：

Aguiar, Ulisses N. ^{[1
]}

de Lima, Sidney G. ^{[1
,2
]}

Rocha, Marcio S. ^{[1
]}

de Freitas, Rivelilson Mendes ^{[1
]}

Oliveira, Talita M. ^{[1
]}

Silva, Raiane M. ^{[2
]}

Moura, Lara C. B. ^{[2
]}

de Almeida, Lorena T. G. ^{[2
]}

机构：

[1] Univ Fed Piaui, Dept Bioquim & Farmacol, BR-64049550 Teresina, PI, Brazil

[2] Univ Fed Piaui, Dept Quim, BR-64049550 Teresina, PI, Brazil

来源：

QUIMICA NOVA | 2014年 / 37卷 / 01期

关键词：

Croton zehntneri; essential oil; beta-cyclodextrin; MOLECULAR MICROCAPSULES; CHEMICAL-COMPOSITION; SOLUBILITY;

D O I：

10.1590/S0100-40422014000100010

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Croton zehntneri, a plant native to northeastern Brazil, is widely used in folk medicine to treat gastrointestinal problems and has rich essential oil content. The essential oil of C. Zehntneri was analyzed by GC-MS, and its inclusion complex with beta-cyclodextrin (beta-CD) was characterized by both vibrational spectroscopy and differential scanning calorimetry (DSC). Estragol was the major component identified in the essential oil by the study. IR spectra indicated an interaction of beta-CD with essential oil from C. zehntneri, a finding corroborated by the stability constant and scanning calorimetry. Microencapsulation within beta-CD has the potential to mask sensory attributes and increase aqueous solubility of oils, thereby improving their applicability as drugs.

引用

页码：50 / 55

页数：6

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