Synthesis of a halo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3′-dimethyl-biphenyl linker using tris(halo-methylphenylene)triazines as building blocks

被引：5

作者：

Kostas, Ioannis D. ^{[1
]}

Andreadaki, Fotini J. ^{[1
]}

Medlycott, Elaine A. ^{[2
]}

Hanan, Garry S. ^{[2
]}

Monflier, Eric ^{[3
]}

机构：

[1] Natl Hellen Res Fdn, Inst Organ & Pharmaceut Chem, Athens 11635, Greece

[2] Univ Montreal, Dept Chim, Montreal, PQ H3T 1J4, Canada

[3] Univ Artois, UMR 8181, Unite Catalyse & Chim Solide, Lens, France

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 16期

关键词：

Dendrimer; Triazine; Cyclotrimerization; Suzuki coupling; Phosphine oxide; Hydroformylation; IN-VIVO TOXICITY; DRUG-DELIVERY; LIQUID-CRYSTALLINE; DENDRIMERS; MELAMINE; HYDROFORMYLATION; PHOSPHINE; CATALYSIS; LIGANDS; OXIDE;

D O I：

10.1016/j.tetlet.2009.02.011

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A tris(bromo-methylphenylene)triazine and its corresponding phosphine oxide derivative have been synthesized; the latter compound was found to be a potent ligand for the hydroformylation reaction. Suzuki coupling of the mono-pinacolboronate derivative of the former compound with a tris(iodo-methylphenylene)triazine was possible at two of the three iodine atoms, yielding a bromo- and iodo-methylphenylene periphery-functionalized triazine-based dendritic molecule with a 3,3 '-dimethyl-bipheny) linker. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：1851 / 1854

页数：4

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