Research-Relevant Clinical Pathology Resources: Emphasis on Mice, Rats, Rabbits, Dogs, Minipigs, and Non-Human Primates

被引:5
作者
Bau-Gaudreault, Liza [1 ]
Arndt, Tara [2 ]
Provencher, Anne [3 ]
Brayton, Cory F. [4 ]
机构
[1] Charles River Labs ULC, Clin Labs, Senneville, PQ, Canada
[2] Labcorp Drug Dev, Madison, WI USA
[3] Charles River Labs ULC, Clin Labs, Sherbrooke, PQ, Canada
[4] Johns Hopkins Univ, Sch Med, Mol & Comparat Pathobiol, Baltimore, MD USA
关键词
Clinical chemistry; clinical pathology; coagulation; cytology; hematology; laboratory animal; safety assessment; toxicology; CARDIAC TROPONIN-I; SERUM BIOCHEMICAL VALUES; SPRAGUE-DAWLEY RATS; CEREBROSPINAL-FLUID COLLECTION; ASSURANCE GUIDELINES CONTROL; URINARY RENAL BIOMARKERS; MACAQUES MACACA-MULATTA; BLOOD-SAMPLE COLLECTION; BRONCHOALVEOLAR LAVAGE FLUID; MARROW DIFFERENTIAL COUNTS;
D O I
10.1093/ilar/ilab028
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Clinical pathology testing for investigative or biomedical research and for preclinical toxicity and safety assessment in laboratory animals is a distinct specialty requiring an understanding of species specific and other influential variables on results and interpretation. This review of clinical pathology principles and testing recommendations in laboratory animal species aims to provide a useful resource for researchers, veterinary specialists, toxicologists, and clinical or anatomic pathologists.
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页码:203 / 222
页数:20
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