Synthesis and antitumor activity of puupehedione and related compounds

被引：82

作者：

Barrero, AF ^{[1
]}

Alvarez-Manzaneda, EJ

Chahboun, R

Cortés, M

Armstrong, V

机构：

[1] Univ Granada, Fac Ciencias, Dept Quim Organ, E-18071 Granada, Spain

[2] Pontificia Univ Catolica Chile, Fac Quim, Dept Quim Organ, Santiago 22, Chile

来源：

TETRAHEDRON | 1999年 / 55卷 / 52期

关键词：

terpenes; antitumour compounds; marine metabolites;

D O I：

10.1016/S0040-4020(99)00992-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first enantiospecific synthesis of bioactive marine puupehedione (2) and related compounds from (-)-sclanol (11) is reported. The antitumor activity of these compounds was assayed and compared with that of the natural products. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：15181 / 15208

页数：28

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