Microviridins D-F, serine protease inhibitors from the cyanobacterium Oscillatoria agardhii (NIES-204)

被引：73
|
作者：
Shin, HJ [1 ]
Murakami, M [1 ]
Matsuda, H [1 ]
Yamaguchi, K [1 ]
机构：
[1] UNIV TOKYO, GRAD SCH AGR & AGR LIFE SCI, MARINE BIOCHEM LAB, BUNKYO KU, TOKYO 113, JAPAN
来源：
TETRAHEDRON | 1996年 / 52卷 / 24期
关键词：
D O I：
10.1016/0040-4020(96)00377-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New serine protease inhibitors, microviridins D, E and F, were isolated from the cyanobacterium Oscillatoria agardhii (NIES-204). Their structures were elucidated to be 1-3 by extensive 2D NMR data and chemical degradation. These dicyclic or cyclic peptides inhibited serine protease potently. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：8159 / 8168
页数：10
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