MCI is associated with deficits in everyday functioning

被引:227
作者
Farias, Sarah T.
Mungas, Dan
Reed, Bruce R.
Harvey, Danielle
Cahn-Weiner, Deborah
DeCarli, Charles
机构
[1] Univ Calif Davis, Dept Neurol, Sacramento, CA 95817 USA
[2] Univ Calif Davis, Dept Publ Hlth Sci, Sacramento, CA 95817 USA
[3] Vet Affairs No Calif Hlth Care Syst, Martinez, CA USA
[4] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA
关键词
mild cognitive impairment (MCI); dertientia; functional impairment;
D O I
10.1097/01.wad.0000213849.51495.d9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The purpose of the present study was to examine the types of impairments in everyday function that accompany mild cognitive impairment (MCI). Data for this study was collected from 434 individuals consecutively evaluated at a university-based Alzheimer's Center. A total of 96 participants were diagnosed with MCI, 105 were cognitively normal, and 233 had dementia. Informant ratings of participants' abilities were obtained across different functional domains reflecting everyday abilities related to memory, language, visual spatial abilities, planning, organization, and divided attention. As expected, the demented group was significantly more impaired than the healthy control and MCI groups across all of the functional domains. The MCI group also showed significantly more functional impairment relative to healthy controls in all of the functional domains. Examination of the effect sizes as a measure of the magnitude of functional impairment in the MCI groups relative to controls showed that the greatest degree of impairment occurred within the Everyday Memory domain. The current findings suggest that individuals with MCI demonstrate deficits in a wide range of everyday functions but that the magnitude of these changes is greatest for those functional abilities that rely heavily on memory.
引用
收藏
页码:217 / 223
页数:7
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