Evidences about combination use of acetylsalicylic acid (aspirin) and clopidogrel in acute coronary syndrome

被引:0
|
作者
Velazquez de Campos, Omaira [1 ]
机构
[1] Cent Univ Venezuela, Fac Med, Escuela Luis Razetti, Dept Ciencias Fisiol,Catedra Farmacol, Caracas, Venezuela
来源
INVESTIGACION CLINICA | 2017年 / 58卷 / 01期
关键词
aspirin; clopidogrel; dual therapy; acute coronary syndrome; stent; fixed combination tablets; PROTON PUMP INHIBITORS; ANTIPLATELET THERAPY; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; HIGH-RISK; INTERVENTION; PREVENTION;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Thromboembolic diseases remain one of the most important causes of morbidity and mortality worldwide. The pathophysiologic mechanism underlying the acute coronary syndromes is coronary thrombosis. That is why the basis of its treatment has focused on antiplatelet, fibrinolytic and anticoagulant drugs. In a significant number of individuals, additional measures must be used, such as, for example, the coronary percutaneous intervention (angioplasty and placement of the so-called intracoronary stents). Aspirin has been regarded as the drug of first choice in the prevention of thromboembolic diseases. The combination aspirin-clopidogrel has represented a highly efficient therapeutic measure for thromboembolic events. The introduction of fixed combination tablets represents a step forward in order to facilitate therapeutic compliance.
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收藏
页码:79 / 91
页数:13
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