The consequences of hypoglycaemia

被引：125

作者：

Amiel, Stephanie A. ^{[1
]}

机构：

[1] Kings Coll London, Fac Life Sci & Med, Sch Life Course Sci, Dept Diabet, London, England

来源：

DIABETOLOGIA | 2021年 / 64卷 / 05期

关键词：

Diabetes mellitus; Hypoglycaemia; Review; PRO-ATHEROTHROMBOTIC BIOMARKERS; RECURRENT SEVERE HYPOGLYCEMIA; ANTECEDENT HYPOGLYCEMIA; COGNITIVE PERFORMANCE; CARDIAC-ARRHYTHMIAS; IMPAIRED AWARENESS; ADULT PATIENTS; TYPE-1; INSULIN; UNAWARENESS;

D O I：

10.1007/s00125-020-05366-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypoglycaemia (blood glucose concentration below the normal range) has been recognised as a complication of insulin treatment from the very first days of the discovery of insulin, and remains a major concern for people with diabetes, their families and healthcare professionals today. Acute hypoglycaemia stimulates a stress response that acts to restore circulating glucose, but plasma glucose concentrations can still fall too low to sustain normal brain function and cardiac rhythm. There are long-term consequences of recurrent hypoglycaemia, which are still not fully understood. This paper reviews our current understanding of the acute and cumulative consequences of hypoglycaemia in insulin-treated diabetes.

引用

页码：963 / 970

页数：8

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