The development of brain magnetic resonance approaches in large animal models for preclinical research

被引：10

作者：

Ella, Arsene ^{[1
,2
]}

Barriere, David A. ^{[1
,3
]}

Adriaensen, Hans ^{[1
]}

Palmer, David N. ^{[4
]}

Melzer, Tracy R. ^{[5
,6
]}

Mitchell, Nadia L. ^{[4
,7
]}

Keller, Matthieu ^{[1
]}

机构：

[1] Univ Tours, Physiol Reprod & Comportements, INRA, CNRS, Tours, France

[2] Univ Cambridge, MRC Cognit & Brain Sci Unit, Cambridge, England

[3] CEA, Neurospin, Gif Sur Yvette, France

[4] Lincoln Univ, Fac Agr & Life Sci, Lincoln, New Zealand

[5] Univ Otago, Dept Med, Christchurch, New Zealand

[6] New Zealand Brain Res Inst, Christchurch, New Zealand

[7] Univ Otago, Dept Radiol, Christchurch, New Zealand

来源：

ANIMAL FRONTIERS | 2019年 / 9卷 / 03期

关键词：

brain; image analysis; magnetic resonance imaging; pathology; NEURONAL CEROID-LIPOFUSCINOSIS; SOUTH HAMPSHIRE SHEEP; ATLAS;

D O I：

10.1093/af/vfz024

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

• Magnetic resonance imaging is a very powerful approach to perform anatomical and functional imaging explorations. • Large animal models are perfectly suited for MRI studies using clinical devices and these tools are currently being developed and improved. • Here we highlight an example of MRI to demonstrate the efficacy of gene therapy in sheep models of Batten disease, a pediatric neurodegenerative disease. © 2019 Oxford University Press. All rights reserved.

引用

页码：44 / 51

页数：8

共 30 条

[1] Induced Pluripotent Stem Cell-Derived Neural Stem Cell Therapy Enhances Recovery in an Ischemic Stroke Pig Model
Baker, Emily W.
Platt, Simon R.
Lau, Vivian W.
Grace, Harrison E.
Holmes, Shannon P.
Wang, Liya
Duberstein, Kylee Jo
Howerth, Elizabeth W.
Kinder, Holly A.
Stice, Steve L.
Hess, David C.
Mao, Hui
West, Franklin D.
[J]. SCIENTIFIC REPORTS, 2017, 7
[2] Boltze J., 2018, J CEREB BLOOD FLOW M, DOI [10.1177/027/1678X18802119, DOI 10.1177/027/1678X18802119]
[3] Use of model organisms for the study of neuronal ceroid lipofuscinosis
Bond, Michael
Holthaus, Sophia-Martha Kleine
Tammen, Imke
Tear, Guy
Russell, Claire
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2013, 1832 (11): : 1842 - 1865
[4] THE TEMPORAL RELATIONSHIP BETWEEN GONADOTROPIN-RELEASING HORMONE (GNRH) AND LUTEINIZING-HORMONE (LH) SECRETION IN OVARIECTOMIZED EWES
CLARKE, IJ
CUMMINS, JT
[J]. ENDOCRINOLOGY, 1982, 111 (05) : 1737 - 1739
[5] Computation of a High-Resolution MRI 3D Stereotaxic Atlas of the Sheep Brain
Ella, Arsene
Delgadillo, Jose A.
Chemineau, Philippe
Keller, Matthieu
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 2017, 525 (03) : 676 - 692
[6] Construction of an MRI 3D high resolution sheep brain template
Ella, Arsene
Keller, Matthieu
[J]. MAGNETIC RESONANCE IMAGING, 2015, 33 (10) : 1329 - 1337
[7] FMRI Mapping of cortical centers following visual stimulation in postnatal pigs of different ages
Fang, MR
Li, JC
Rudd, JA
Wai, SM
Yew, JCC
Yew, DT
[J]. LIFE SCIENCES, 2006, 78 (11) : 1197 - 1201
[8] A new large animal model of CLN5 neuronal ceroid lipofuscinosis in Borderdale sheep is caused by a nucleotide substitution at a consensus splice site (c.571+1G > A) leading to excision of exon 3
Frugier, Tony
Mitchell, Nadia L.
Tammen, Imke
Houweling, Peter J.
Arthur, Donald G.
Kay, Graham W.
Van Diggelen, Otto P.
Jolly, Robert D.
Palmer, David N.
[J]. NEUROBIOLOGY OF DISEASE, 2008, 29 (02) : 306 - 315
[9] Mapping of Sheep Sensory Cortex With a Novel Microelectrocorticography Grid
Gierthmuehlen, Mortimer
Wang, Xi
Gkogkidis, Alexis
Henle, Christian
Fischer, Joerg
Fehrenbacher, Thomas
Kohler, Fabian
Raab, Markus
Mader, Irina
Kuehn, Celina
Foerster, Katharina
Haberstroh, Joerg
Freiman, Thomas M.
Stieglitz, Thomas
Rickert, Joern
Schuettler, Martin
Ball, Tonio
[J]. JOURNAL OF COMPARATIVE NEUROLOGY, 2014, 522 (16) : 3590 - 3608
[10] Harding Jane E, 2004, Pediatr Endocrinol Rev, V2, P182

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