Mouse xenograft models vs GEM models for human cancer therapeutics

被引:293
作者
Richmond, Ann [1 ,2 ]
Su, Yingjun [1 ,2 ]
机构
[1] Vanderbilt Univ, Dept Canc Biol, Sch Med, Nashville, TN 37235 USA
[2] VA Med Ctr, Nashville, TN USA
关键词
D O I
10.1242/dmm.000976
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:78 / 82
页数:5
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共 18 条
[11]   The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications [J].
Mitsiades, N ;
Mitsiades, CS ;
Richardson, PG ;
Poulaki, V ;
Tai, YT ;
Chauhan, D ;
Fanourakis, G ;
Gu, XS ;
Bailey, C ;
Joseph, M ;
Libermann, TA ;
Schlossman, R ;
Munshi, NC ;
Hideshima, T ;
Anderson, KC .
BLOOD, 2003, 101 (06) :2377-2380
[12]  
MOREAU P, 2008, BLOOD REV 0611
[13]   Establishment of human tumor xenografts in immunodeficient mice [J].
Morton, Christopher L. ;
Houghton, Peter J. .
NATURE PROTOCOLS, 2007, 2 (02) :247-250
[14]   Receptor activator of NF-κB ligand, macrophage inflammatory protein-1αa, and the proteasome -: Novel therapeutic targets in myeloma [J].
Oyajobi, BO ;
Mundy, GR .
CANCER, 2003, 97 (03) :813-817
[15]   CORRELATION OF DRUG RESPONSE IN PATIENTS AND IN THE CLONOGENIC-ASSAY WITH SOLID HUMAN TUMOR XENOGRAFTS [J].
SCHOLZ, CC ;
BERGER, DP ;
WINTERHALTER, BR ;
HENSS, H ;
FIEBIG, HH .
EUROPEAN JOURNAL OF CANCER, 1990, 26 (08) :901-905
[16]   Weekly paclitaxel plus Herceptin in metastatic breast cancer patients who relapse after stem-cell transplant [J].
Sporn, JR ;
Bilgrami, SA .
ANNALS OF ONCOLOGY, 1999, 10 (10) :1259-1260
[17]   Murine models to evaluate novel and conventional therapeutic strategies for cancer [J].
Talmadge, James E. ;
Singh, Rakesh K. ;
Fidler, Isaiah J. ;
Raz, Avraham .
AMERICAN JOURNAL OF PATHOLOGY, 2007, 170 (03) :793-804
[18]   A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer [J].
Yang, JC ;
Haworth, L ;
Sherry, RM ;
Hwu, P ;
Schwartzentruber, DJ ;
Topalian, SL ;
Steinberg, SM ;
Chen, HX ;
Rosenberg, SA .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (05) :427-434