Refractory Celiac Disease Type II: A Case Report and Literature Review

被引：9
作者：
Chibbar, Richa [1 ,2 ]
Nostedt, Jordan [3 ]
Mihalicz, Dana [3 ]
Deschenes, Jean [4 ]
McLean, Ross [5 ]
Dieleman, Levinus A. [1 ]
机构：
[1] Univ Alberta, Dept Med, Div Gastroenterol, Edmonton, AB, Canada
[2] Beth Israel Deaconess Med Ctr, Dept Med, Div Gastro, Boston, MA 02215 USA
[3] Univ Alberta, Div Gen Surg, Dept Surg, Edmonton, AB, Canada
[4] Univ Alberta, Dept Lab Med & Pathol, Cross Canc Inst, Edmonton, AB, Canada
[5] Univ Alberta, Royal Alexandra Hosp, Dept Lab Med, Edmonton, AB, Canada
来源：
FRONTIERS IN MEDICINE | 2020年 / 7卷
关键词：
refractory celiac disease; EATL; ulcerative jejunitis; sigmoid perforation; immunophenotyping; STEM-CELL TRANSPLANTATION; THERAPY; SPRUE; BUDESONIDE; INFLIXIMAB; SURVIVAL; AZATHIOPRINE; MANAGEMENT; LYMPHOMA; PATIENT;
D O I：
10.3389/fmed.2020.564875
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We present an unusual case of 68-year-old male, who presented with acute abdomen, ulcerative jejunitis with perforation, and 2 months later with perforation of the sigmoid colon. We will also discuss difficulties in the delay in diagnosis of refractory celiac disease (RCD), specifically the atypical presentation, multiple surgeries, the consecutive failure of distinct therapeutic options, and multiple complications that occurred within the 3 months since first presentation.
引用
收藏
页数：7
相关论文
共 52 条
[1]   Cross-sectional imaging in refractory celiac disease [J].
Al-Bawardy, Badr ;
Barlow, John M. ;
Vasconcelos, Rogerio N. ;
Kim, Sarasa T. ;
Bruining, David H. ;
Hansel, Stephanie L. ;
Sheedy, Shannon P. ;
Murray, Joseph A. ;
Rubio-Tapia, Alberto ;
Rajan, Elizabeth ;
Fidler, Jeff L. ;
Fletcher, Joel G. .
ABDOMINAL RADIOLOGY, 2017, 42 (02) :389-395
[2]   Survival in refractory coeliac disease and enteropathyassociated T-cell lymphoma: retrospective evaluation of single-centre experience [J].
Al-Toma, A. ;
Verbeek, W. H. M. ;
Hadithi, M. ;
von Blomberg, B. M. E. ;
Mulder, C. J. J. .
GUT, 2007, 56 (10) :1373-1378
[3]   Disappointing outcome of autologous stem cell transplantation for enteropathy-associated T-cell lymphoma [J].
Al-Toma, A. ;
Verbeek, W. H. M. ;
Visser, O. J. ;
Kuijpers, K. C. ;
Oudejans, J. J. ;
Kluin-Nelemans, H. C. ;
Mulder, C. J. J. ;
Huijgens, P. C. .
DIGESTIVE AND LIVER DISEASE, 2007, 39 (07) :634-641
[4]   Human leukocyte antigen-DQ2 homozygosity and the development of refractory Celiac disease and enteropathy-associated T-cell lymphoma [J].
Al-Toma, A ;
Goerres, MS ;
Meijer, JWR ;
Peña, AS ;
Crusius, JBA ;
Mulder, CJJ .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (03) :315-319
[5]  
Al-toma A, 2007, J GASTROINTEST LIVER, V16, P57
[6]   Autologous hematopoietic stem cell transplantation in refractory celiac disease with aberrant T cells [J].
Al-toma, Abdulbaqi ;
Visser, Otto J. ;
van Roessel, Hyacintha M. ;
von Blomberg, B. Mary E. ;
Verbeek, Wieke H. M. ;
Scholten, Petra E. T. ;
Ossenkoppele, Gert J. ;
Huijgens, Peter C. ;
Mulder, Chris J. J. .
BLOOD, 2007, 109 (05) :2243-2249
[7]   Cladribine therapy in refractory celiac disease with aberrant T cells [J].
Al-Toma, Abdulbaqi ;
Goerres, Marije S. ;
Meijer, Jos W. R. ;
Von Blomberg, B. Mary E. ;
Wahab, Peter J. ;
Kerckhaert, Jo A. M. ;
Mulder, Chris J. J. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2006, 4 (11) :1322-1327
[8]   Budesonide in the treatment of refractory celiac disease [J].
Brar, Pardeep ;
Lee, Susie ;
Lewis, Suzanne ;
Egbuna, Ikenna ;
Bhagat, Govind ;
Green, Peter H. R. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2007, 102 (10) :2265-2269
[9]   Celiac disease: a comprehensive current review [J].
Caio, Giacomo ;
Volta, Umberto ;
Sapone, Anna ;
Leffler, Daniel A. ;
De Giorgio, Roberto ;
Catassi, Carlo ;
Fasano, Alessio .
BMC MEDICINE, 2019, 17 (1)
[10]   Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma [J].
Cellier, C ;
Delabesse, E ;
Helmer, C ;
Patey, N ;
Matuchansky, C ;
Jabri, B ;
Macintyre, E ;
Cerf-Bensussan, N ;
Brousse, N .
LANCET, 2000, 356 (9225) :203-208
123456