Selective Effect of Neurocognition on Different Theory of Mind Domains in First-Episode Psychosis

被引：19

作者：

Fernandez-Gonzalo, Sol ^{[1
,2
]}

Jodar, Merce ^{[2
,3
,4
]}

Pousa, Esther ^{[2
,4
,5
]}

Turon, Marc ^{[1
,2
]}

Garcia, Rebeca ^{[4
,5
]}

Hernandez Rambla, Carla ^{[4
,5
]}

Palao, Diego ^{[4
,5
,6
]}

机构：

[1] Univ Autonoma Barcelona, Res Dept, Fundacio Parc Tauli, Parc Tauli Sabadell,Univ Inst,Univ Hosp, Sabadell, Spain

[2] Univ Autonoma Barcelona, Dept Clin & Hlth Psychol, Psychopathol & Neuropsychol Res Unit, Bellaterra, Spain

[3] Neurol Dept Parc Tauli, Sabadell, Spain

[4] Univ Autonoma Barcelona, Univ Hosp, Bellaterra, Spain

[5] Parc Tauli, Dept Mental Hlth, Sabadell, Spain

[6] Univ Autonoma Barcelona, Dept Psychiat & Forens Med, E-08193 Barcelona, Spain

来源：

JOURNAL OF NERVOUS AND MENTAL DISEASE | 2014年 / 202卷 / 08期

关键词：

Social cognition; executive functions; theory of mind; first-episode schizophrenia/schizoaffective disorder; SOCIAL COGNITIVE IMPAIRMENTS; 1ST EPISODE; NEGATIVE SYMPTOMS; SCHIZOPHRENIA; DEFICITS; PEOPLE; SYMPTOMATOLOGY; DISSOCIATION; COMPONENTS; REMISSION;

D O I：

10.1097/NMD.0000000000000164

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The aim of this study was to investigate the influence of neurocognition on affective and cognitive theory of mind (ToM) tasks in early phases of psychosis. In a cross-sectional study of 60 first-episode schizophrenia/schizoaffective disorder patients, the implication of neurocognition in first- and second-order ToM stories, Hinting Task, and Reading the Mind in the Eyes Test (RMET) was analyzed. Regression models were used, controlling for clinical symptoms and antipsychotic dose. Spatial span backward (odds ratio [OR], 0.34; p = 0.01) and intrusions in the Rey Auditory Verbal Learning Test (OR, 4.86; p = 0.04) were the best factors to predict second-order ToM failure. Trail Making Test B (B = 0.01; p = 0.04) and negative symptoms (B = 0.09; p = 0.01) predicted Hinting task performance while Block design (B = 0.1; p = 0.04) was related to RMET outcome. Executive functions and clinical symptoms were related to ToM performance in first-episode schizophrenia patients, although different patterns of relationship were observed in each ToM task.

引用

页码：576 / 582

页数：7

共 75 条

[31] Exploring 'theory of mind' in people with schizophrenia [J].