Pressurized liquid extraction and liquid chromatography-tandem mass spectrometry applied to determine iodinated X-ray contrast media in sewage sludge

被引：6
作者：
Echeverria, S. [1 ]
Borrull, F. [1 ]
Pocurull, E. [1 ]
Fontanals, N. [1 ]
机构：
[1] Univ Rovira & Virgili, Dept Analyt Chem & Organ Chem, E-43007 Tarragona, Spain
来源：
ANALYTICA CHIMICA ACTA | 2014年 / 844卷
关键词：
Iodinated X-ray contrast media; Sewage sludge; Pressurized liquid extraction; Liquid chromatography-tandem mass spectrometry; ENVIRONMENTAL RISK-ASSESSMENT; PERSONAL-CARE PRODUCTS; TREATED WASTE-WATER; MUSK FRAGRANCES; IOPROMIDE ULTRAVIST; ANAEROBIC-DIGESTION; PHARMACEUTICALS; FATE; SYSTEMS; CONTAMINANTS;
D O I：
10.1016/j.aca.2014.05.055
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Pressurized liquid extraction (PLE) has been successfully applied for the first time to the extraction of five iodinated X-ray contrast media from sludge. Once optimized all PLE parameters, the extract has been analyzed by liquid chromatography-tandem mass spectrometry, being the method developed sensible enough to reach limit of quantifications (LOQs) of 25 mu g kg (1) (d.w.). The developed method has been applied to the analysis of sludge from urban sewage treatment plants and although some compounds such as iopromide, diatrizoic acid and iopamidol have been identified, their concentrations have been lower than their LOQs. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：75 / 79
页数：5
相关论文
共 25 条
[1]   Rapid analysis of iodinated X-ray contrast media in secondary and tertiary treated wastewater by direct injection liquid chromatography-tandem mass spectrometry [J].
Busetti, Francesco ;
Linge, Kathryn L. ;
Blythe, Justin W. ;
Heitz, Anna .
JOURNAL OF CHROMATOGRAPHY A, 2008, 1213 (02) :200-208
[2]   Occurrence of iodinated X-ray contrast media in indirect potable reuse systems [J].
Busetti, Francesco ;
Linge, Kathryn L. ;
Rodriguez, Clemencia ;
Heitz, Anna .
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 2010, 45 (05) :542-548
[3]   Fate of pharmaceutical and personal care products (PPCPs) during anaerobic digestion of sewage sludge [J].
Carballa, Marta ;
Omil, Francisco ;
Ternes, Thomas ;
Lema, Juan M. .
WATER RESEARCH, 2007, 41 (10) :2139-2150
[4]   X-ray contrast media - an overview [J].
Christiansen, C .
TOXICOLOGY, 2005, 209 (02) :185-187
[5]   Determination of iodinated X-ray contrast media in sewage by solid-phase extraction and liquid chromatography tandem mass spectrometry [J].
Echeverria, S. ;
Borrull, F. ;
Fontanals, N. ;
Pocurull, E. .
TALANTA, 2013, 116 :931-936
[6]   Occurrence of psychoactive compounds and their metabolites in groundwater downgradient of a decommissioned sewage farm in Berlin (Germany) [J].
Hass, Ulrike ;
Duennbier, Uwe ;
Massmann, Gudrun .
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2012, 19 (06) :2096-2106
[7]   A sensitive method for the determination of iodine containing diagnostic agents in aqueous matrices using LC-electrospray-tandem-MS detection [J].
Hirsch, R ;
Ternes, TA ;
Lindart, A ;
Haberer, K ;
Wilken, RD .
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2000, 366 (08) :835-841
[8]   Biodegradation of the iodinated X-ray contrast media diatrizoate and iopromide [J].
Kalsch, W .
SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 225 (1-2) :143-153
[9]   Occurrence of Iodinated X-ray Contrast Media and Their Biotransformation Products in the Urban Water Cycle [J].
Kormos, Jennifer Lynne ;
Schulz, Manoj ;
Ternes, Thomas A. .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2011, 45 (20) :8723-8732
[10]   Hospital Wastewater Treatment by Membrane Bioreactor: Performance and Efficiency for Organic Micropollutant Elimination [J].
Kovalova, Lubomira ;
Siegrist, Hansruedi ;
Singer, Heinz ;
Wittmer, Anita ;
McArdell, Christa S. .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2012, 46 (03) :1536-1545
123