Pulmonary metastasectomy in colorectal cancer: Time for a trial

被引：40

作者：

Treasure, T. ^{[1
]}

Fallowfield, L. ^{[2
]}

Farewell, V. ^{[3
]}

Ferry, D. ^{[4
]}

Lees, B. ^{[5
]}

Leonard, P. ^{[6
]}

Macbeth, F. ^{[7
]}

Utley, M. ^{[1
]}

机构：

[1] UCL, Clin Operat Res Unit, Dept Math, London WC1H 0BT, England

[2] Univ Sussex, Brighton & Sussex Med School, CRUK Sussex Psychosocial Oncol Grp, Brighton BN1 9QG, E Sussex, England

[3] Univ Forvie Site, Inst Publ Hlth, MRC Biostat Unit, Cambridge CB2 0SR, England

[4] New Cross Hosp, Dept Oncol, Wolverhampton WV10 0QP, W Midlands, England

[5] Royal Brompton Hosp, Clin Trials & Evaluat Unit, London SW3 6NP, England

[6] Southend Univ Hosp NHS Fdn Trust, Westcliff On Sea SS0 0RY, Essex, England

[7] Natl Inst Hlth & Clin Excellence, London WC1V 6NA, England

来源：

EJSO | 2009年 / 35卷 / 07期

关键词：

Colorectal cancer; Pulmonary metastasectomy; Randomised controlled trial; MESOTHELIOMA; RESECTION; SERIES;

D O I：

10.1016/j.ejso.2008.12.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pulmonary metastasectomy is undertaken for a range of cancers. The questions we raise here are specifically related to colorectal cancer, the commonest tumour for which pulmonary metastasectomy is undertaken. The primary objective of metastasectomy is to increase survival. There are no randomised trials in support of this practice nor are there any other forms of controlled studies. We present a critical look at the assumption of efficacy for this surgery and propose that a trial is needed and suggest a trial design. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：686 / 689

页数：4

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