共 25 条
Can 18F-FDG PET improve the evaluation of suspicious breast lesions on MRI?
被引:20
作者:

Bitencourt, Almir G. V.
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Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil

Lima, Eduardo N. P.
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Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil

Chojniak, Rubens
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Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil

Marques, Elvira F.
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Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil

Souza, Juliana A.
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Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil

Andrade, Wesley P.
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机构:
Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Mastol, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil

Guimaraes, Marcos D.
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Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil
机构:
[1] Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Diagnost Imaging, BR-01509010 Sao Paulo, Brazil
[2] Hosp AC Camargo Fund Antonio Prudente, Fdn Antonio Prudente, Dept Mastol, BR-01509010 Sao Paulo, Brazil
关键词:
Breast cancer;
Magnetic resonance imaging;
Positron-emission tomography;
Prone position;
Fluorodeoxyglucose F18;
POSITRON-EMISSION-TOMOGRAPHY;
FDG-PET;
F-18-FDG PET/CT;
CANCER;
MAMMOGRAPHY;
METAANALYSIS;
DIAGNOSIS;
ESTROGEN;
FUSION;
D O I:
10.1016/j.ejrad.2014.05.021
中图分类号:
R8 [特种医学];
R445 [影像诊断学];
学科分类号:
1002 ;
100207 ;
1009 ;
摘要:
Objective: To evaluate the impact of adding 18F-fluorine-2-deoxy-D-glucose (FDG) positron emission tomography (PET) in the evaluation of suspicious breast lesions on magnetic resonance imaging (MRI). Methods: Sixty patients with suspicious breast lesions on MRI were selected to perform a PET-CT in prone position, dedicated to the evaluation of the breasts. The areas with increased 18F-FDG concentration relative to normal parenchyma were considered positive on PET-CT. Fusion of PET and MRI images (PET-MRI) was performed on a dedicated workstation to better locate corresponding lesions, and its findings were compared with histological results. Results: 76 lesions were evaluated, including 64 mass lesions (84.2%) and 12 non-mass lesions (15.8%). Lesions mean diameter on MRI was 29.6 +/- 19.2 mm (range 6-94 mm). PET-CT showed increased metabolically activity on 57 lesions (75.0%), with mean maximum SUV of 5.7 +/- 5.0 (range 0.8-23.1). On histopathology, there were 17 (22.4%) benign and 59 (79.7%) malignant lesions. Considering all lesions, PET-MRI fusion provided 89.8% sensitivity, 76.5% specificity and 86.8% accuracy. Considering only mass lesions higher than 10 mm, PET-MRI fusion provided 95.8% sensitivity, 83.3% specificity and 93.3% accuracy. Conclusion: The inclusion of 18F-FDG PET on the evaluation of suspicious breast lesions on MRI helped to differentiate benign from malignant breast lesions, especially for mass lesions with a diameter higher than 10 mm. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
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页码:1381 / 1386
页数:6
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