Polymer interfaces used in electrochemical DNA-based biosensors

被引：15
作者：
Galandova, Julia [1 ]
Labuda, Jan [1 ]
机构：
[1] Slovak Tech Univ, Fac Chem & Food Technol, Inst Analyt Chem, Bratislava 81237, Slovakia
来源：
CHEMICAL PAPERS | 2009年 / 63卷 / 01期
关键词：
DNA biosensor; electrode; polymer; nanocomposite; surface modification; PEPTIDE NUCLEIC-ACID; CARBON NANOTUBES; CONDUCTING POLYMERS; ELECTRICAL-CONDUCTIVITY; AMPEROMETRIC DETECTION; ELECTROACTIVE POLYMER; LABEL-FREE; PROBE DNA; HYBRIDIZATION; SURFACE;
D O I：
10.2478/s11696-008-0083-2
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Nowadays DNA-based biosensors represent powerful tools for the study of DNA sequence, DNA chemical interactions and damage. Among them, biosensors with an electrochemical signal transducer play the most important role. The performance of a biosensor strongly depends on the method of a biorecognition element being attached to the electrode. This review refers to polymer materials being used to create a DNA-electrode interface. The main terminology is given in Introduction followed by a description of polymers and polymer-based nanocomposites and their electrochemical properties. A comprehensive table reports examples of the electrochemical detection of DNA immobilized on the polymer matrix. Finally, a short survey is given. (C) 2008 Institute of Chemistry, Slovak Academy of Sciences
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页码：1 / 14
页数：14
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