Expanding donor pool by utilizing deceased donors with snake envenoming

被引:1
作者
Meshram, Hari Shankar [1 ]
Kute, Vivek [1 ]
Patel, Himanshu [1 ]
Chauhan, Sanshriti [1 ]
Desai, Sudeep [1 ]
机构
[1] IKDRC ITS, Dept Nephrol & Transplantat, Ahmadabad, Gujarat, India
关键词
deceased donor; developing nation; organ wastage; snakebite; TRANSPLANTATION;
D O I
10.1111/ctr.14135
中图分类号
R61 [外科手术学];
学科分类号
摘要
In India, the deceased kidney transplant program is still in its preliminary stage, and accepting deceased donors with snakebite is just a forward step to expand the donor pool. We report here the outcome of 8 successful renal transplantations from brain-dead donors who died from a neurotoxic snakebite. We accepted them as donors as they had no evidence of hemotoxic snakebite. 7 recipients did well. 1 died due to sepsis with a functioning graft. 1 required renal biopsy that showed acute tubular necrosis. 1 required re-exploration due to graft collection due to a surgical issue. Patient and graft survival in follow-up were similar to other matched deceased donors in our center. According to our experience, utilizing brain-dead donors who died from a neurotoxic snakebite is safe and may dramatically expand the donor pool especially in countries where death due to snakebite is high in numbers.
引用
收藏
页数:6
相关论文
共 14 条
  • [1] Abraham Georgi, 2016, World J Transplant, V6, P331, DOI 10.5500/wjt.v6.i2.331
  • [2] Pronase treatment facilitates alloantibody flow cytometric and cytotoxic crossmatching in the presence of rituximab
    Bearden, CA
    Agarwal, A
    Book, BK
    Sidner, RA
    Gebel, HM
    Bray, RA
    Pescovitz, MD
    [J]. HUMAN IMMUNOLOGY, 2004, 65 (08) : 803 - 809
  • [3] THE FLOW CYTOMETRIC CROSSMATCH - DUAL-COLOR ANALYSIS OF T-CELL AND B-CELL REACTIVITIES
    BRAY, RA
    LEBECK, LK
    GEBEL, HM
    [J]. TRANSPLANTATION, 1989, 48 (05) : 834 - 840
  • [4] Dhananjaya BL, 2015, TOXINOLOGY, P379, DOI 10.1007/978-94-007-6386-9_39
  • [5] HYPOFIBRINOGENEMIA AFTER ECHIS-COLORATA BITE IN MAN
    DVILANSKY, A
    BIRAN, H
    [J]. ACTA HAEMATOLOGICA, 1973, 49 (02) : 123 - 127
  • [6] The Global Burden of Snakebite: A Literature Analysis and Modelling Based on Regional Estimates of Envenoming and Deaths
    Kasturiratne, Anuradhani
    Wickremasinghe, A. Rajitha
    de Silva, Nilanthi
    Gunawardena, N. Kithsiri
    Pathmeswaran, Arunasalam
    Premaratna, Ranjan
    Savioli, Lorenzo
    Lalloo, David G.
    de Silva, H. Janaka
    [J]. PLOS MEDICINE, 2008, 5 (11) : 1591 - 1604
  • [7] Successful Renal Transplantation From a Brain-Dead Deceased Donor Who Died From Snakebite: A Case Report
    Kute, V. B.
    Vanikar, A. V.
    Patel, H. V.
    Gumber, M. R.
    Shah, P. R.
    Engineer, D. P.
    Modi, P. R.
    Rizvi, S. J.
    Trivedi, H. L.
    [J]. TRANSPLANTATION PROCEEDINGS, 2013, 45 (07) : 2801 - 2803
  • [8] Prolonged cardiac allograft survival in presensitized rats after a high activity Yunnan-cobra venom factor therapy
    Li, R.
    Chen, G.
    Guo, H.
    Wang, D. W.
    Xie, L.
    Wang, S. S.
    Wang, W. Y.
    Xiong, Y. L.
    Chen, S.
    [J]. TRANSPLANTATION PROCEEDINGS, 2006, 38 (10) : 3263 - 3265
  • [9] Development of sandwich ELISA and lateral flow strip assays for diagnosing clinically significant snakebite in Taiwan
    Liu, Chien-Chun
    Yu, Jau-Song
    Wang, Po-Jung
    Hsiao, Yung-Chin
    Liu, Chien-Hsin
    Chen, Yen-Chia
    Lai, Pei-Fang
    Hsu, Chih-Po
    Fann, Wen-Chih
    Lin, Chih-Chuan
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2018, 12 (12):
  • [10] Diagnosis of snake envenomation using a simple phospholipase A2 assay
    Maduwage, Kalana
    O'Leary, Margaret A.
    Isbister, Geoffrey K.
    [J]. SCIENTIFIC REPORTS, 2014, 4