Conformation of protonated guanine nucleotides via infrared multiphoton dissociation spectroscopy: Observation of rotamers in the anti-conformation

被引：3

作者：

Asami, Hiroya ^{[1
]}

Saigusa, Hiroyuki ^{[2
]}

Kohno, Jun-ya ^{[1
]}

机构：

[1] Gakushuin Univ, Fac Sci, Dept Chem, Toshima Ku, 1-5-1 Mejiro, Tokyo 1718588, Japan

[2] Yokohama City Univ, Sch Sci, Kanazawa Ku, 22-2 Seto, Yokohama, Kanagawa 2360027, Japan

来源：

CHEMICAL PHYSICS LETTERS | 2020年 / 756卷

关键词：

Infrared multiphoton dissociation spectroscopy; Nucleotide; IR ablation; Droplet beam; Ab initio calculation; IR-LASER ABLATION; DOUBLE-RESONANCE SPECTROSCOPY; PHOTODISSOCIATION SPECTROSCOPY; DROPLET BEAM; NUCLEOSIDES; GUANOSINE; ROTATION; TRAP; IONS; ACID;

D O I：

10.1016/j.cplett.2020.137828

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Guanosine 5'-monophosphate (GMP) is a component in RNA, which functions as a messenger in biological systems. Infrared multiphoton dissociation (IRMPD) spectroscopy, combined with IR-laser ablation of a droplet beam, reveals that the most stable conformer of gas-phase protonated GMP has a keto form and an anti-conformation. This includes two types of rotamers with different orientations of OH groups in the sugar ring. This suggests that our own laser ablation of droplet beam method promotes conformation-selective IRMPD spectroscopy with an effective cooling system in the gas phase.

引用

页数：4

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