Comparative killing rates of fluoroquinolones and cell wall-active agents

被引：28

作者：

Fung-Tomc, JC ^{[1
]}

Gradelski, E ^{[1
]}

Valera, L ^{[1
]}

Kolek, B ^{[1
]}

Bonner, DP ^{[1
]}

机构：

[1] Bristol Myers Squibb Co, Dept Microbiol 104, Wallingford, CT 06492 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2000年 / 44卷 / 05期

关键词：

D O I：

10.1128/AAC.44.5.1377-1380.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Killing rates of fluoroquinolones, beta-lactams, and vancomycin were compared against Enterobacteriaceae, Staphylococcus aureus, pneumococci, streptococci, and Enterococcus faecalis. The times required for fluoroquinolones to decrease viability by 3 log(10) were 1.5 h for Enterobacteriaceae, 4 to 6 h for staphylococci, and greater than or equal to 6 h for streptococci and enterococci. Thus, the rate of killing by fluoroquinolones is organism group dependent; overall, they killed more rapidly than beta-lactams and vancomycin.

引用

页码：1377 / 1380

页数：4

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