The Biotechnological Potential of Secondary Metabolites from Marine Bacteria

被引:49
|
作者
Andryukov, Boris [1 ]
Mikhailov, Valery [2 ]
Besednova, Nataly [1 ]
机构
[1] GP Somov Res Inst Epidemiol & Microbiol, Vladivostok 690087, Russia
[2] Russian Acad Sci, GB Elyakov Pacific Inst Bioorgan Chem, Far Eastern Branch, Vladivostok 690022, Russia
关键词
biotechnologies; marine bacteria; secondary metabolites; non-ribosomal biosynthesis; antibacterial strategies; STRUCTURE ELUCIDATION; SURFACE COLONIZATION; NATURAL-PRODUCTS; DEPSIPEPTIDES; BIOSYNTHESIS; PEPTIDES; DATABASE; PROBIOTICS; PROSPECTS; PATHWAYS;
D O I
10.3390/jmse7060176
中图分类号
U6 [水路运输]; P75 [海洋工程];
学科分类号
0814 ; 081505 ; 0824 ; 082401 ;
摘要
Marine habitats are a rich source of molecules of biological interest. In particular, marine bacteria attract attention with their ability to synthesize structurally diverse classes of bioactive secondary metabolites with high biotechnological potential. The last decades were marked by numerous discoveries of biomolecules of bacterial symbionts, which have long been considered metabolites of marine animals. Many compounds isolated from marine bacteria are unique in their structure and biological activity. Their study has made a significant contribution to the discovery and production of new natural antimicrobial agents. Identifying the mechanisms and potential of this type of metabolite production in marine bacteria has become one of the noteworthy trends in modern biotechnology. This path has become not only one of the most promising approaches to the development of new antibiotics, but also a potential target for controlling the viability of pathogenic bacteria.
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页数:16
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