Acid-promoted denitrogenative Pd-catalyzed addition of arylhydrazines with nitriles at room temperature

被引：31

作者：

Cheng, Kai ^{[1
]}

Wang, Guofang ^{[1
]}

Meng, Mengting ^{[1
]}

Qi, Chenze ^{[1
]}

机构：

[1] Shaoxing Univ, Zhejiang Key Lab Alternat Technol Fine Chem Proc, Shaoxing 312000, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2017年 / 4卷 / 03期

基金：

中国国家自然科学基金;

关键词：

CROSS-COUPLING REACTION; N BOND-CLEAVAGE; CARBONYLATIVE SUZUKI REACTIONS; C-H ACTIVATION; ARYL KETONES; ARYLBORONIC ACIDS; RADICAL ARYLATION; TOSYL ARYLHYDRAZINES; CARBON NUCLEOPHILES; CARBOXYLIC-ACIDS;

D O I：

10.1039/c6qo00634e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Pd(TFA)(2)-catalyzed denitrogenative addition proceeded with selective C-N bond cleavage of arylhydrazines with nitriles in the presence of DABCO and HFBA under air at room temperature. Aryl ketones could be easily synthesized via the hydrolysis of the ketimine moiety generated in situ without the need for additional water.

引用

页码：398 / 403

页数：6

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