Trimethylchlorosilane: A novel activating reagent in nucleotide synthesis via the phosphoramidite route

被引:13
|
作者
Dabkowski, W
Tworowska, I
Michalski, J
Cramer, F
机构
[1] POLISH ACAD SCI, CTR MOL & MACROMOL STUDIES, PL-90363 LODZ, POLAND
[2] MAX PLANCK INST EXPT MED, D-37075 GOTTINGEN, GERMANY
关键词
D O I
10.1039/a701924f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Trimethylchlorosilane (TMSCl) is a remarkably efficient activator in the reaction of phosphorus(III) amides with nucleosides to give phosphorus(In) esters in excellent yield.
引用
收藏
页码:877 / 878
页数:2
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