Septic Ketoacidosis

被引:13
作者
Nakamura, Kensuke [1 ,2 ]
Inokuchi, Ryota [2 ]
Doi, Kent [2 ,3 ]
Fukuda, Tatsuma [1 ,2 ]
Tokunaga, Kurato [1 ,2 ]
Nakajima, Susumu [2 ]
Noiri, Eisei [3 ]
Yahagi, Naoki [2 ]
机构
[1] Hitachi Gen Hosp, Dept Emergency & Crit Care Med, Hitachi, Ibaraki, Japan
[2] Tokyo Univ Hosp, Dept Emergency & Crit Care Med, Tokyo, Japan
[3] Tokyo Univ Hosp, Dept Hemodialysis & Apheresis, Tokyo, Japan
关键词
septic ketoacidosis; sepsis; ketoacidosis; strong ion gap; CRITICALLY-ILL PATIENTS; INTENSIVE-CARE-UNIT; STRONG ION GAP; METABOLIC-ACIDOSIS; SEVERE SEPSIS; UNMEASURED ANIONS; KETOSIS; HUMANS; SHOCK;
D O I
10.2169/internalmedicine.53.1791
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Various unmeasured anions other than lactate appear in the blood of septic patients, including ketones. However, the occurrence of sepsis-induced ketoacidosis without diabetes mellitus has not been reported to date. We herein describe severe ketoacidosis in a patient with septic shock despite the absence of diabetes, alcohol and starvation. A 76-year-old woman presented with septic shock due to acute obstructive cholangitis. She exhibited ketoacidosis and a remarkably strong ion gap, except for ketones. Sepsis alone may lead to ketoacidosis in patients without diabetes under specific conditions. The accumulation of ketones and other strong anions can occur in cases involving a decreased metabolic function. There may be a pathological condition called septic ketoacidosis.
引用
收藏
页码:1071 / 1073
页数:3
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