Efficient Synthesis of Homoallylic Alcohols/Amines from Allyltributylstannane and Carbonyl Compounds/Imines Using Iodine as Catalyst Under Acetic Acid-Water Medium

被引：2

作者：

Kalita, Pabitra Kumar ^{[1
]}

Borthakur, Susanta Kumar ^{[1
]}

Das, Runumi ^{[1
]}

Choudhury, Chandan Jyothi ^{[1
]}

机构：

[1] Arya Vidyapeeth Coll, Dept Chem, Gauhati 781016, Assam, India

来源：

SYNTHETIC COMMUNICATIONS | 2015年 / 45卷 / 21期

关键词：

Aldimines; allylation; carbonyl compounds; iodine; BARBIER-TYPE ALLYLATION; INDIUM-MEDIATED ALLYLATION; FULLY AQUEOUS-MEDIA; CHEMOSELECTIVE ALLYLATION; 3-COMPONENT SYNTHESIS; ORGANIC-SYNTHESIS; ALDEHYDES; KETONES; IMINES; AMINES;

D O I：

10.1080/00397911.2015.1085574

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper describes a general method for the synthesis of homoallylic alcohols and amines by nucleophilic addition reaction of allyltributylstannane to carbonyl compounds and aldimines where iodine acts as a catalyst in H2O/acetic acid (1:1) medium. Only 10mol% of I-2 is required for various organic transformations. By using this process, various homoallylic alcohols and amines are produced in good to excellent yields.

引用

页码：2444 / 2453

页数：10

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