Analysis of Residual Furan in Human Blood Using Solid Phase Microextraction-Gas Chromatography/Mass Spectrometry (SPME-GC/MS)
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作者:
Lee, Yun-Kyung
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Dongguk Univ, Dept Food Sci & Technol, Seoul 100715, South KoreaDongguk Univ, Dept Food Sci & Technol, Seoul 100715, South Korea
Lee, Yun-Kyung
[1
]
Jung, Seung-Won
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Dongguk Univ, Dept Food Sci & Technol, Seoul 100715, South KoreaDongguk Univ, Dept Food Sci & Technol, Seoul 100715, South Korea
Jung, Seung-Won
[1
]
Lee, Sung Joon
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Korea Univ, Div Food Sci, Coll Life Sci & Biotechnol, Inst Biomed Sci & Safety, Seoul 136713, South KoreaDongguk Univ, Dept Food Sci & Technol, Seoul 100715, South Korea
Lee, Sung Joon
[2
]
Lee, Kwang-Geun
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Dongguk Univ, Dept Food Sci & Technol, Seoul 100715, South KoreaDongguk Univ, Dept Food Sci & Technol, Seoul 100715, South Korea
Lee, Kwang-Geun
[1
]
机构:
[1] Dongguk Univ, Dept Food Sci & Technol, Seoul 100715, South Korea
[2] Korea Univ, Div Food Sci, Coll Life Sci & Biotechnol, Inst Biomed Sci & Safety, Seoul 136713, South Korea
For all accurate risk assessment of furan, a potential human carcinogen, levels must be determined ill human blood plasma using a simple and robust assay. Ill thiS study solid phase microextraction-gas chromatography/mass spectrometry (SPME-GC/MS) Was Used to analyze blood plasma levels of furan ill 100 healthy individuals Who consumed a normal diet. The subjects were 30 to 70 years of age and 51% were women. Ultimately, an analytical method was established tor analyzing furan in human blood. The limit of quantification (LOQ) and furan recovery rate in blood were 1.0 ppb arld 104%, respectively. Finally, furan was detected in 21 individuals (13 males, 8 females) with levels ranging up to 17.86 ppb (ng furan/g food).
机构:
Henan Univ, Coll Life Sci, Kaifeng 475004, Peoples R China
Henan Univ, Inst Chinese Mat Med, Kaifeng 475004, Peoples R China
Henan Univ, Minsheng Coll, Kaifeng 475004, Peoples R ChinaHenan Univ, Coll Life Sci, Kaifeng 475004, Peoples R China
Wei, Jin-Feng
Yin, Zhen-hua
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Henan Univ, Inst Chinese Mat Med, Kaifeng 475004, Peoples R ChinaHenan Univ, Coll Life Sci, Kaifeng 475004, Peoples R China
Yin, Zhen-hua
Shang, Fu-De
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Henan Univ, Coll Life Sci, Kaifeng 475004, Peoples R ChinaHenan Univ, Coll Life Sci, Kaifeng 475004, Peoples R China
Shang, Fu-De
AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY,
2012,
6
(33):
: 2484
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2487
机构:
Korea Res Inst Stand & Sci, Div Chem Metrol & Mat Evaluat, Taejon 305340, South KoreaKorea Res Inst Stand & Sci, Div Chem Metrol & Mat Evaluat, Taejon 305340, South Korea
Lee, JH
Hwang, SM
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机构:Korea Res Inst Stand & Sci, Div Chem Metrol & Mat Evaluat, Taejon 305340, South Korea
Hwang, SM
Lee, DW
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机构:Korea Res Inst Stand & Sci, Div Chem Metrol & Mat Evaluat, Taejon 305340, South Korea
Lee, DW
Heo, GS
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机构:Korea Res Inst Stand & Sci, Div Chem Metrol & Mat Evaluat, Taejon 305340, South Korea
机构:
Univ Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, MalaysiaUniv Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, Malaysia
Ho, C. W.
Aida, W. M. Wan
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Univ Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, MalaysiaUniv Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, Malaysia
Aida, W. M. Wan
Maskat, M. Y.
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Univ Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, MalaysiaUniv Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, Malaysia
Maskat, M. Y.
Osman, H.
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Univ Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, MalaysiaUniv Kebangsaan Malaysia, Fac Sci & Technol, Sch Chem Sci & Food Technol, Bangi 43600, Malaysia