Temperature increase induced by modulated electrohyperthermia (oncothermia®) in the anesthetized pig liver

被引:8
作者
Balogh, Lajos [1 ]
Polyak, Andras [1 ]
Postenyi, Zita [1 ]
Kovacs-Haasz, Veronika [1 ]
Gyongy, Miklos [2 ]
Thuroczy, Julianna [3 ]
机构
[1] Natl FJC Res Inst Radiobiol & Radiohyg, Dept Nucl Med & Natl Biol Sci, Budapest, Hungary
[2] Pazmany Peter Catholic Univ, Fac Informat Technol & Bion, Jedlik Labs, Budapest, Hungary
[3] Szent Istvan Univ, Dept Small Anim Reprod & Obstet, Fac Vet, Budapest, Hungary
关键词
Deep-tissue temperature enhancement; hyperthermia; modulated electrohyperthermia (oncothermia (R)); WHOLE-BODY HYPERTHERMIA; DOGS; TISSUE; TUMORS;
D O I
10.4103/0973-1482.197561
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aim of Study: Is to show the intrahepatic temperature development in anesthetized pig. Materials and Methods: Temperature development in the liver of anesthetized pig is measured to study the thermal effects of capacitive coupled energy transfer. The treatment was made by modulated electrohyperthermia (mEHT, trade name: oncothermia (R)), controlled by a fluoroptical temperature sensing positioned by the ultrasound-guided process. Various fits of coupling were studied. Results: The intrahepatic temperature at the end of the treatment ranged 40.5-44.8 degrees C, while the skin temperature ranged 36.8-41.8 degrees C depending on the coupling arrangement. Conclusion: mEHT is a feasible method to deliver deep heat to the liver of an anesthetized pig.
引用
收藏
页码:1153 / 1159
页数:7
相关论文
共 21 条
[1]   SELECTIVE DESTRUCTION OF CANCERS AFTER EXPOSURE TO HEAT [J].
CRILE, G .
ANNALS OF SURGERY, 1962, 156 (03) :404-&
[2]   Cell membrane thermal gradients induced by electromagnetic fields [J].
Garner, Allen L. ;
Deminsky, Maxim ;
Neculaes, V. Bogdan ;
Chashihin, V. ;
Knizhnik, Andrey ;
Potapkin, Boris .
JOURNAL OF APPLIED PHYSICS, 2013, 113 (21)
[3]  
GRIER RL, 1980, J AM VET MED ASSOC, V177, P227
[4]  
GRIER RL, 1980, J AM VET MED ASSOC, V177, P55
[5]  
Jackson PGG., 2007, Handbook of pig medicine
[6]  
KAINER RA, 1980, J AM VET MED ASSOC, V176, P356
[7]  
KAINER RA, 1978, S P MANAGEMENT BOVIN, P51
[8]  
LORD PF, 1981, CANCER RES, V41, P4331
[9]  
Matteucci ML, 2000, CLIN CANCER RES, V6, P3748
[10]  
Neumann SM, 1980, P AM COLL VET OPHTHA, P1