Preparation of 6-chloro-5-fluoroindole via the use of palladium and copper-mediated heterocyclisations

被引：20

作者：

Adams, DR ^{[1
]}

Duncton, MAJ ^{[1
]}

Roffey, JRA ^{[1
]}

Spencer, J ^{[1
]}

机构：

[1] Vernalis Res Ltd, Dept Chem, Woking RG41 5UA, Surrey, England

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 42期

关键词：

indoles; palladium and compounds; catalysis; coupling reactions;

D O I：

10.1016/S0040-4039(02)01758-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title indole, the heterocyclic core of the 5-HT2C receptor agonist Ro 60-0175, was prepared by it modification to the Stille indole synthesis, or by the method of Gonzalez and co-workers. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：7581 / 7583

页数：3

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