Bring population mansion based on STR variation within Y-chromosome SNP-haplogroups

被引:0
作者
Zhivotovsky, L. A. [1 ]
机构
[1] RAS, NI Vavilov Inst Gen Genet, Moscow, Russia
来源
Proceedings of the Fourth International Conference on Bioinformatics of Genome Regulation and Structure, Vol 2 | 2004年
关键词
human evolution; DNA markers; STRs; SNPs; dating; mathematical models; statistical methods;
D O I
暂无
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: Dating divergence within- and between DNA-lineages is of great importance for revealing historic information from observed DNA variation in human populations. The increasing amount of data on Y-chromosome SNI's and STRs require adequate methods for estimation of population expansion time. Such methods should necessarily involve mathematical models that describe evolution of DNA variation, and statistical methods to estimate the dates of population events. Results: Dynamic models of population divergence under mutation, genetic drift and migration are analyzed. Estimates of the dynamic parameters are introduced and applied to several data sets on worldwide human populations.
引用
收藏
页码:248 / 250
页数:3
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