Global and regional dissemination and evolution of Burkholderia pseudomallei

被引：125

作者：

Chewapreecha, Claire ^{[1
,2
,3
]}

Holden, Matthew T. G. ^{[2
,4
]}

Vehkala, Minna ^{[5
]}

Valimaki, Niko ^{[6
]}

Yang, Zhirong ^{[5
]}

Harris, Simon R. ^{[2
]}

Mather, Alison E. ^{[7
]}

Tuanyok, Apichai ^{[8
]}

De Smet, Birgit ^{[9
,10
]}

Le Hello, Simon ^{[11
]}

Bizet, Chantal ^{[12
]}

Mayo, Mark ^{[13
,14
]}

Wuthiekanun, Vanaporn ^{[15
]}

Limmathurotsakul, Direk ^{[15
,16
,17
]}

Phetsouvanh, Rattanaphone ^{[18
]}

Spratt, Brian G. ^{[19
]}

Corander, Jukka ^{[5
,20
]}

Keim, Paul ^{[21
]}

Dougan, Gordon ^{[2
]}

Dance, David A. B. ^{[17
,18
,22
]}

Currie, Bart J.

Parkhill, Julian ^{[2
]}

Peacock, Sharon J. ^{[1
,2
,22
]}

机构：

[1] Univ Cambridge, Dept Med, Cambridge CB2 0QQ, England

[2] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

[3] King Mongkuts Univ Technol Thonburi, Sch Bioresources & Technol, Bioinformat & Syst Biol Program, Bangkok 10140, Thailand

[4] Univ St Andrews, Sch Med, St Andrews KY16 9AJ, Fife, Scotland

[5] Univ Helsinki, Dept Math & Sci, Helsinki 00100, Finland

[6] Univ Helsinki, Dept Med & Clin Genet, Genome Scale Biol Res Program, Helsinki 00100, Finland

[7] Univ Cambridge, Dept Vet Med, Cambridge CB3 0ES, England

[8] Univ Florida, Emerging Pathogens Inst, Gainesville, FL 32611 USA

[9] Inst Trop Med, B-2000 Antwerp, Belgium

[10] Univ Ghent, Fac Sci, Lab Microbiol, B-9000 Ghent, Belgium

[11] Inst Pasteur, Dept Infect & Epidemiol, Enter Bacteria Pathogen Unit, F-75015 Paris, France

[12] Inst Pasteur, Dept Microbiol, Collect Inst Pasteur, F-75015 Paris, France

[13] Royal Darwin Hosp, Darwin, NT 0811, Australia

[14] Charles Darwin Univ, Menzies Sch Hlth Res, Global & Trop Hlth Div, Darwin, NT 0811, Australia

[15] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res, Bangkok 10400, Thailand

[16] Mahidol Univ, Fac Trop Med, Dept Trop Hyg, Bangkok 10400, Thailand

[17] Univ Oxford, Ctr Trop Med & Global Hlth, Oxford OX3 7FZ, England

[18] Mahosot Hosp, Microbiol Lab, Lao Oxford Mahosot Hosp Wellcome Trust Res Unit, Viangchan, Laos

[19] Imperial Coll, Dept Infect Dis Epidemiol, London SW7 2AZ, England

[20] Univ Oslo, Dept Biostat, N-0313 Oslo, Norway

[21] Northren Arizona Univ, Ctr Microbial Genet & Genom, Flagstaff, AZ 86011 USA

[22] London Sch Hyg & Trop Med, London WC1E 7HT, England

来源：

NATURE MICROBIOLOGY | 2017年 / 2卷 / 04期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会; 英国惠康基金;

关键词：

MELIOIDOSIS; VIRULENCE; MRSA; TOOL;

D O I：

10.1038/nmicrobiol.2016.263

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The environmental bacterium Burkholderia pseudomallei causes an estimated 165,000 cases of human melioidosis per year worldwide and is also classified as a biothreat agent. We used whole genome sequences of 469 B. pseudomallei isolates from 30 countries collected over 79 years to explore its geographic transmission. Our data point to Australia as an early reservoir, with transmission to Southeast Asia followed by onward transmission to South Asia and East Asia. Repeated reintroductions were observed within the Malay Peninsula and between countries bordered by the Mekong River. Our data support an African origin of the Central and South American isolates with introduction of B. pseudomallei into the Americas between 1650 and 1850, providing a temporal link with the slave trade. We also identified geographically distinct genes/variants in Australasian or Southeast Asian isolates alone, with virulence-associated genes being among those over-represented. This provides a potential explanation for clinical manifestations of melioidosis that are geographically restricted.

引用

页数：8

共 60 条

[31] Social representations of history in Malaysia and Singapore: On the relationship between national and ethnic identity
Liu, JH
Lawrence, B
Ward, C
Abraham, S
[J]. ASIAN JOURNAL OF SOCIAL PSYCHOLOGY, 2002, 5 (01) : 3 - 20
[32] Klebsiella pneumoniae Carbapenemase (KPC)-Producing K-pneumoniae at a Single Institution: Insights into Endemicity from Whole-Genome Sequencing
Mathers, Amy J.
Stoesser, Nicole
Sheppard, Anna E.
Pankhurst, Louise
Giess, Adam
Yeh, Anthony J.
Didelot, Xavier
Turner, Stephen D.
Sebra, Robert
Kasarskis, Andrew
Peto, Tim
Crook, Derrick
Sifri, Costi D.
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (03) : 1661 - 1668
[33] The effect of genetic structure on molecular dating and tests for temporal signal
Murray, Gemma G. R.
Wang, Fang
Harrison, Ewan M.
Paterson, Gavin K.
Mather, Alison E.
Harris, Simon R.
Holmes, Mark A.
Rambaut, Andrew
Welch, John J.
[J]. METHODS IN ECOLOGY AND EVOLUTION, 2016, 7 (01): : 80 - 89
[34] Burkholderia pseudomallei sequencing identifies genomic clades with distinct recombination, accessory, and epigenetic profiles
Nandi, Tannistha
Holden, Mathew T. G.
Didelot, Xavier
Mehershahi, Kurosh
Boddey, Justin A.
Beacham, Ifor
Peak, Ian
Harting, John
Baybayan, Primo
Guo, Yan
Wang, Susana
How, Lee Chee
Sim, Bernice
Essex-Lopresti, Angela
Sarkar-Tyson, Mitali
Nelson, Michelle
Smither, Sophie
Ong, Catherine
Aw, Lay Tin
Hoon, Chua Hui
Michell, Stephen
Studholme, David J.
Titball, Richard
Chen, Swaine L.
Parkhill, Julian
Tan, Patrick
[J]. GENOME RESEARCH, 2015, 25 (01) : 129 - 141
[35] A Genomic Survey of Positive Selection in Burkholderia pseudomallei Provides Insights into the Evolution of Accidental Virulence
Nandi, Tannistha
Ong, Catherine
Singh, Arvind Pratap
Boddey, Justin
Atkins, Timothy
Sarkar-Tyson, Mitali
Essex-Lopresti, Angela E.
Chua, Hui Hoon
Pearson, Talima
Kreisberg, Jason F.
Nilsson, Christina
Ariyaratne, Pramila
Ronning, Catherine
Losada, Liliana
Ruan, Yijun
Sung, Wing-Kin
Woods, Donald
Titball, Richard W.
Beacham, Ifor
Peak, Ian
Keim, Paul
Nierman, William C.
Tan, Patrick
[J]. PLOS PATHOGENS, 2010, 6 (04) : 1 - 15
[36] Nguyen ThiDieu., 1999, The Mekong River and the Struggle for Indochina: Water, War and Peace
[37] The Condition-Dependent Transcriptional Landscape of Burkholderia pseudomallei
Ooi, Wen Fong
Ong, Catherine
Nandi, Tannistha
Kreisberg, Jason F.
Chua, Hui Hoon
Sun, Guangwen
Chen, Yahua
Mueller, Claudia
Conejero, Laura
Eshaghi, Majid
Ang, Roy Moh Lik
Liu, Jianhua
Sobral, Bruno W.
Korbsrisate, Sunee
Gan, Yunn Hwen
Titball, Richard W.
Bancroft, Gregory J.
Valade, Eric
Tan, Patrick
[J]. PLOS GENETICS, 2013, 9 (09):
[38] Page A.J., 2016, Microb. Genomics.
[39] Roary: rapid large-scale prokaryote pan genome analysis
Page, Andrew J.
Cummins, Carla A.
Hunt, Martin
Wong, Vanessa K.
Reuter, Sandra
Holden, Matthew T. G.
Fookes, Maria
Falush, Daniel
Keane, Jacqueline A.
Parkhill, Julian
[J]. BIOINFORMATICS, 2015, 31 (22) : 3691 - 3693
[40] Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer
Pearson, Talima
Giffard, Philip
Beckstrom-Sternberg, Stephen
Auerbach, Raymond
Hornstra, Heidie
Tuanyok, Apichai
Price, Erin P.
Glass, Mindy B.
Leadem, Benjamin
Beckstrom-Sternberg, James S.
Allan, Gerard J.
Foster, Jeffrey T.
Wagner, David M.
Okinaka, Richard T.
Sim, Siew Hoon
Pearson, Ofori
Wu, Zaining
Chang, Jean
Kaul, Rajinder
Hoffmaster, Alex R.
Brettin, Thomas S.
Robison, Richard A.
Mayo, Mark
Gee, Jay E.
Tan, Patrick
Currie, Bart J.
Keim, Paul
[J]. BMC BIOLOGY, 2009, 7

← 1 2 3 4 5 6 →