Synthesis of a silica-bonded bovine serum albumin carbonyl chiral stationary phase for high-performance liquid chromatographic resolution of enantiomers

被引：0
作者：
Feng, S
Zhang, Q
Zou, HF [1 ]
Wang, JD
Chen, XM
Zhang, ZZ
机构：
[1] Xinjiang Univ, Dept Chem, Urumqi 830024, Peoples R China
[2] Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
来源：
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE | 2002年 / 23卷 / 07期
关键词：
chiral separation; bovine serum albumin; aminopropyl silica gel; 1,1-carbonyldiimidazole; chiral stationary phase;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An HPLC chiral stationary phase was synthesized by the in situ covalent immobilization of bovine serum albumin on a aminopropyl silica packed column activated with 1,1-carbonyldiimidazole in a short time. The effects of mobile phase pH and the content of 1-propanol on k' and alpha of D,L-tryptophan were investigated, and the resolution of seven chiral compounds was successfully achieved.
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页码：1251 / 1254
页数：4
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