Pathophysiology of ischemic placental disease

被引:140
作者
Roberts, James M. [1 ,2 ]
机构
[1] Magee Womens Res Inst, Pittsburgh, PA 15213 USA
[2] Univ Pittsburgh, Dept Obstet Gynecol & Reprod Sci, Pittsburgh, PA USA
关键词
placenta; preeclampsia; intrauterine growth restriction; premature birth; placenta ischemia; EXTRAVILLOUS TROPHOBLAST INVASION; OXIDATIVE STRESS; SPIRAL ARTERIES; ENDOTHELIAL DYSFUNCTION; DECIDUA BASALIS; ACUTE ATHEROSIS; GROWTH-FACTOR; PREECLAMPSIA; PREGNANCY; WOMEN;
D O I
10.1053/j.semperi.2014.03.005
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The pregnancy disorders associated with placental ischemia share many similar pathological and pathophysiological features and are associated with the failure to deliver adequate nutrients and oxygen to the placenta. The origins of this deficiency are a subject of intense study. In this article, I review the genesis and consequences of this pathology addressing the similarities and the differences with the different disorders and addressing current gaps in our knowledge. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:139 / 145
页数:7
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