The hallmarks of breast cancer by Raman spectroscopy

被引：51

作者：

Abramczyk, H. ^{[1
,2
]}

Surmacki, J. ^{[1
]}

Brozek-Pluska, B. ^{[1
]}

Morawiec, Z. ^{[3
]}

Tazbir, M. ^{[3
]}

机构：

[1] Tech Univ Lodz, Inst Appl Radiat Chem, Lab Laser Mol Spect, Fac Chem, PL-93590 Lodz, Poland

[2] Max Born Inst, D-12489 Berlin, Germany

[3] Kopernik Hosp, Oncol Ward, Lodz, Poland

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2009年 / 924卷

关键词：

Breast cancer; Raman spectroscopy; PCA; TISSUES; LIQUID; BETA;

D O I：

10.1016/j.molstruc.2008.12.055

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This paper presents new biological results on ex vivo breast tissue based on Raman spectroscopy and demonstrates its power as diagnostic tool with the key advantage in breast cancer research. The results presented here demonstrate the ability of Raman spectroscopy to accurately characterize cancer tissue and distinguish between normal, malignant and benign types. The goal of the paper is to develop the diagnostic ability of Raman spectroscopy in order to find an optical marker of cancer in the breast tissue. Applications of Raman spectroscopy in breast cancer research are in the early stages of development in the world. To the best of our knowledge, this paper is one of the most statistically reliable reports (1100 spectra, 99 patients) on Raman spectroscopy-based diagnosis of breast cancers among the world women population. (c) 2009 Elsevier B.V. All rights reserved.

引用

页码：175 / 182

页数：8

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