Familial Hypercholesterolemia in a Healthy Elderly Population

被引：8

作者：

Lacaze, Paul ^{[1
]}

Sebra, Robert ^{[2
,3
]}

Riaz, Moeen ^{[1
]}

Hooper, Amanda J. ^{[4
,5
,6
]}

Tiller, Jane ^{[1
]}

Bakshi, Andrew ^{[1
]}

Woods, Robyn L. ^{[1
]}

Tonkin, Andrew M. ^{[1
]}

Reid, Christopher M. ^{[1
,7
]}

Murray, Anne M. ^{[8
]}

Nicholls, Stephen J. ^{[9
,10
]}

Watts, Gerald F. ^{[4
,11
]}

Schadt, Eric ^{[2
,3
]}

McNeil, John J. ^{[1
]}

机构：

[1] Monash Univ, Sch Publ Hlth & Prevent Med, Dept Epidemiol & Prevent Med, Level 5,99 Commercial Rd, Melbourne, Vic 3004, Australia

[2] Icahn Sch Med Mt Sinai, Icahn Inst Data Sci & Genom Technol, Dept Genet & Genom Sci, New York, NY 10029 USA

[3] Sema4, Stamford, CT USA

[4] Univ Western Australia, Fac Med & Hlth Sci, Sch Med, Perth, WA, Australia

[5] Royal Perth Hosp, PathWest Lab Med WA, Dept Clin Biochem, Perth, WA, Australia

[6] Fiona Stanley Hosp Network, Perth, WA, Australia

[7] Curtin Univ, Sch Publ Hlth, Perth, WA, Australia

[8] Hennepin Healthcare, Hennepin Healthcare Res Inst, Berman Ctr Outcomes & Clin Res, Minneapolis, MN USA

[9] Monash Univ, Monash Cardiovasc Res Ctr, Clayton, Vic, Australia

[10] Monash Hlth, MonashHeart, Clayton, Vic, Australia

[11] Royal Perth Hosp, Lipid Disorders Clin, Dept Cardiol, Perth, WA, Australia

来源：

CIRCULATION-GENOMIC AND PRECISION MEDICINE | 2020年 / 13卷 / 04期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

alleles; familial hypercholesterolemia; genetic testing; genetics; humans;

D O I：

10.1161/CIRCGEN.120.002938

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页数：3

共 6 条

[1] Genetic identification of familial hypercholesterolemia within a single US health care system [J].

Abul-Husn, Noura S. ;

Manickam, Kandamurugu ;

Jones, Laney K. ;

Wright, Eric A. ;

Hartzel, Dustin N. ;

Gonzaga-Jauregui, Claudia ;

O'Dushlaine, Colm ;

Leader, Joseph B. ;

Kirchner, H. Lester ;

Lindbuchler, D'Andra M. ;

Barr, Marci L. ;

Giovanni, Monica A. ;

Ritchie, Marylyn D. ;

Overton, John D. ;

Reid, Jeffrey G. ;

Metpally, Raghu P. R. ;

Wardeh, Amr H. ;

Borecki, Ingrid B. ;

Yancopoulos, George D. ;

Baras, Aris ;

Shuldiner, Alan R. ;

Gottesman, Omri ;

Ledbetter, David H. ;

Carey, David J. ;

Dewey, Frederick E. ;

Murray, Michael F. .

SCIENCE, 2016, 354 (6319)

[2] Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease [J].

Khera, Amit V. ;

Emdin, Connor A. ;

Drake, Isabel ;

Natarajan, Pradeep ;

Bick, Alexander G. ;

Cook, Nancy R. ;

Chasman, Daniel I. ;

Baber, Usman ;

Mehran, Roxana ;

Rader, Daniel J. ;

Fuster, Valentin ;

Boerwinkle, Eric ;

Melander, Olle ;

Orho-Melander, Marju ;

Ridker, Paul M. ;

Kathiresan, Sekar .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (24) :2349-2358

[3] Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly [J].

McNeil, J. J. ;

Wolfe, R. ;

Woods, R. L. ;

Tonkin, A. M. ;

Donnan, G. A. ;

Nelson, M. R. ;

Reid, C. M. ;

Lockery, J. E. ;

Kirpach, B. ;

Storey, E. ;

Shah, R. C. ;

Williamson, J. D. ;

Margolis, K. L. ;

Ernst, M. E. ;

Abhayaratna, W. P. ;

Stocks, N. ;

Fitzgerald, S. M. ;

Orchard, S. G. ;

Trevaks, R. E. ;

Beilin, L. J. ;

Johnston, C. I. ;

Ryan, J. ;

Radziszewska, B. ;

Jelinek, M. ;

Malik, M. ;

Eaton, C. B. ;

Brauer, D. ;

Cloud, G. ;

Wood, E. M. ;

Mahady, S. E. ;

Satterfield, S. ;

Grimm, R. ;

Murray, A. M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (16) :1509-1518

[4] Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study [J].

McNeil, John J. ;

Woods, Robyn L. ;

Nelson, Mark R. ;

Murray, Anne M. ;

Reid, Christopher M. ;

Kirpach, Brenda ;

Storey, Elsdon ;

Shah, Raj C. ;

Wolfe, Rory S. ;

Tonkin, Andrew M. ;

Newman, Anne B. ;

Williamson, Jeff D. ;

Lockery, Jessica E. ;

Margolis, Karen L. ;

Ernst, Michael E. ;

Abhayaratna, Walter P. ;

Stocks, Nigel ;

Fitzgerald, Sharyn M. ;

Trevaks, Ruth E. ;

Orchard, Suzanne G. ;

Beilin, Lawrence J. ;

Donnan, Geoffrey A. ;

Gibbs, Peter ;

Johnston, Colin I. ;

Grimm, Richard H. .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2017, 72 (11) :1586-1593

[5] Heterozygous Familial Hypercholesterolemia [J].

Onorato, Angela ;

Sturm, Amy C. .

CIRCULATION, 2016, 133 (14) :E587-E589

[6] Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology [J].

Richards, Sue ;

Aziz, Nazneen ;

Bale, Sherri ;

Bick, David ;

Das, Soma ;

Gastier-Foster, Julie ;

Grody, Wayne W. ;

Hegde, Madhuri ;

Lyon, Elaine ;

Spector, Elaine ;

Voelkerding, Karl ;

Rehm, Heidi L. .

GENETICS IN MEDICINE, 2015, 17 (05) :405-424

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