Therapy with interferon plus ribavirin in hemodialysis patient with virus C hepatitis

Traditionally, the treatment of virical hepatitis C (positive Polymerase Chain Reaccion -RCP-) was with Interferon. A combination of Interferon plus Ribavin are producing better results on last years. Currently, Ribavirin is not indicated for patients with Chronic Kidney Disease because exist high risk of several anaemia. In a few cases, this treatment is producing good results with previously dosifications adjust. We show a case of a 28 years old man with Chronic Kidney Disease on treatment with periodical hemodialysis and chronic hepatopathy HCV Positive RNA HCV (> 1,000,000 copies/ml) and persistent transaminase elevation. Before kidney transplantation, we decided to use Interferon (3,000,000 IU/48 hours) and Rivavirin (200 mg/24 hours) treatment. After 15 days, exists normal transaminase values and HCV RNA was negative. The patient required temporally suspension of Rivavirin and two red blood cells transfusions due to several anaemic; and was reintroduced 200 mg/48 h posthemodialysis. The patient did not present any complication again, and could be treated for 14 months. After next 11 months of evolution the patient have normal rates of liver function and negative HCV RNA values.