Epigenetic silencing of HTLV-1 expression by the HBZ RNA through interference with the basal transcription machinery

被引：18

作者：

Gazon, Helene ^{[1
,2
]}

Chauhan, Pradeep Singh ^{[1
,2
]}

Porquet, Florent ^{[1
,2
]}

Hoffmann, Gabriela Brunsting ^{[1
,2
]}

Accolla, Roberto ^{[3
]}

Willems, Luc ^{[1
,2
]}

机构：

[1] Interdisciplinary Cluster Appl Genoprote GIGA, Mol & Cellular Epigenet, Liege, Belgium

[2] Mol Biol Teaching & Res Ctr TERRA, Gembloux, Belgium

[3] Univ Insubria, Sch Med, Dept Med & Surg, Varese, Italy

来源：

BLOOD ADVANCES | 2020年 / 4卷 / 21期

关键词：

PROTEIN; CELLS;

D O I：

10.1182/bloodadvances.2020001675

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：5574 / 5579

页数：6

共 22 条

[1] HTLV-1-associated myelopathy/tropical spastic paraparesis [J].

Bangham, Charles R. M. ;

Araujo, Abelardo ;

Yamano, Yoshihisa ;

Taylor, Graham P. .

NATURE REVIEWS DISEASE PRIMERS, 2015, 1

[2] Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) [J].

Baratella, Marco ;

Forlani, Greta ;

Raval, Goutham U. ;

Tedeschi, Alessandra ;

Gout, Olivier ;

Gessain, Antoine ;

Tosi, Giovanna ;

Accolla, Roberto S. .

PLOS NEGLECTED TROPICAL DISEASES, 2017, 11 (01)

[3]

Billman Martin R, 2017, Wellcome Open Res, V2, P87, DOI 10.12688/wellcomeopenres.12469.2

[4] The HTLV-1 hbz antisense gene indirectly promotes tax expression via down-regulation of p30II mRNA [J].

Choudhary, Gunjan ;

Ratner, Lee .

VIROLOGY, 2011, 410 (02) :307-315

[5] Chromatin Isolation by RNA Purification (ChIRP) [J].

Chu, Ci ;

Quinn, Jeffrey ;

Chang, Howard Y. .

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2012, (61)

[6] An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ [J].

Clerc, Isabelle ;

Polakowski, Nicholas ;

Andre-Arpin, Charlotte ;

Cook, Pamela ;

Barbeau, Benoit ;

Mesnard, Jean-Michel ;

Lemasson, Isabelle .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (35) :23903-23913

[7] Human T-Lymphotropic Virus type 1 infection in an Indigenous Australian population: epidemiological insights from a hospital-based cohort study [J].

Einsiedel, Lloyd ;

Woodman, Richard J. ;

Flynn, Maria ;

Wilson, Kim ;

Cassar, Olivier ;

Gessain, Antoine .

BMC PUBLIC HEALTH, 2016, 16

[8] Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia [J].

El Hajj, Hiba ;

El-Sabban, Marwan ;

Hasegawa, Hideki ;

Zaatari, Ghazi ;

Ablain, Julien ;

Saab, Shahrazad T. ;

Janin, Anne ;

Mahfouz, Rami ;

Nasr, Rihab ;

Kfoury, Youmna ;

Nicot, Christophe ;

Hermine, Olivier ;

Hall, William ;

de The, Hugues ;

Bazarbachi, Ali .

JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (13) :2785-2792

[9] The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription [J].

Gaudray, G ;

Gachon, F ;

Basbous, J ;

Biard-Piechaczyk, M ;

Devaux, C ;

Mesnard, JM .

JOURNAL OF VIROLOGY, 2002, 76 (24) :12813-12822

[10] Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients [J].

Gazon, Helene ;

Belrose, Gildas ;

Terol, Marie ;

Meniane, Jean-Come ;

Mesnard, Jean-Michel ;

Cesaire, Raymond ;

Peloponese, Jean-Marie, Jr. .

ONCOTARGET, 2016, 7 (21) :30258-30275

← 1 2 3 →