Early detection of paracetamol toxicity using circulating liver microRNA and markers of cell necrosis

被引：39

作者：

Dear, James W. ^{[1
,2
]}

Antoine, Daniel J. ^{[3
]}

Starkey-Lewis, Philip ^{[3
]}

Goldring, Christopher E. ^{[3
]}

Park, B. Kevin ^{[3
]}

机构：

[1] Royal Infirm Edinburgh NHS Trust, Natl Poisons Informat Serv Edinburgh, Edinburgh, Midlothian, Scotland

[2] Univ Edinburgh, British Heart Fdn, Ctr Cardiovasc Sci, Edinburgh EH16 4TJ, Midlothian, Scotland

[3] Univ Liverpool, Dept Mol & Clin Pharmacol, MRC Ctr Drug Safety Sci, Liverpool L69 3BX, Merseyside, England

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 2014年 / 77卷 / 05期

基金：

英国医学研究理事会;

关键词：

BIOMARKERS; KERATIN-18;

D O I：

10.1111/bcp.12214

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：904 / 905

页数：2

共 7 条

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[2] RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity (Publication with Expression of Concern. See vol. 73, pg. 1297, 2020) (Publication with Expression of Concern. See vol. 69, pg. 1402, 2018) (Retracted article. See vol. 73, pg. 1297, 2020) [J].

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[4] Management of paracetamol poisoning [J].

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[5] Treating acetaminophen overdose: thresholds, costs and uncertainties [J].

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[6] Circulating MicroRNAs as Potential Markers of Human Drug-Induced Liver Injury [J].

Lewis, Philip J. Starkey ;

Dear, James ;

Platt, Vivien ;

Simpson, Kenneth J. ;

Craig, Darren G. N. ;

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Dhaun, Neeraj ;

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[7] Circulating microRNAs, potential biomarkers for drug-induced liver injury [J].

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