Multiple Myeloma, Version 3.2017 Clinical Practice Guidelines in Oncology

被引：141

作者：

Kumar, Shaji K. ^{[1
]}

Callander, Natalie S. ^{[2
]}

Alsina, Melissa ^{[3
]}

Atanackovic, Djordje ^{[4
]}

Biermann, J. Sybil ^{[5
]}

Chandler, Jason C. ^{[6
]}

Costello, Caitlin ^{[7
]}

Faiman, Matthew ^{[8
,9
]}

Fung, Henry C. ^{[10
]}

Gasparetto, Cristina ^{[11
]}

Godby, Kelly ^{[12
]}

Hofmeister, Craig ^{[13
,14
]}

Holmberg, Leona ^{[15
]}

Holstein, Sarah ^{[16
]}

Huff, Carol Ann ^{[17
]}

Kassim, Adetola ^{[18
]}

Liedtke, Michaela ^{[19
]}

Martin, Thomas ^{[20
]}

Omel, James

Raje, Noopur ^{[21
]}

Reu, Frederic J. ^{[22
,23
]}

Singhal, Seema ^{[24
]}

Somlo, George ^{[25
]}

Stockerl-Goldstein, Keith ^{[26
,27
]}

Treon, Steven P. ^{[28
]}

Weber, Donna ^{[29
]}

Yahalom, Joachim ^{[30
]}

Shead, Dorothy A.

Kumar, Rashmi

机构：

[1] Mayo Clin, Ctr Canc, Rochester, MN USA

[2] Univ Wisconsin, Carbone Canc Ctr, Madison, WI 53706 USA

[3] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[4] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[5] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[6] Univ Tennessee, St Jude Childrens Res Hosp, Hlth Sci Ctr, Knoxville, TN 37996 USA

[7] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA 92103 USA

[8] Univ Hosp Seidman, Ctr Canc, Case Comprehens Canc Ctr, Cleveland, OH USA

[9] Cleveland Clin, Taussig Canc Inst, Cleveland, OH USA

[10] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA

[11] Duke Canc Inst, Durham, NC USA

[12] Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL USA

[13] Ohio State Univ, James Canc Hosp, Ctr Comprehens Canc, Columbus, OH 43210 USA

[14] Solove Res Inst, Columbus, OH USA

[15] Fred Hutchinson Canc Res Ctr, Seattle Canc Care Alliance, Seattle, WA 98104 USA

[16] Fred Pamela Buffett Canc Ctr, Omaha, NE USA

[17] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[18] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[19] Stanford Canc Inst, Stanford, CA USA

[20] UCSF, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[21] Massachusetts Gen Hosp, Ctr Canc, Boston, MA USA

[22] Univ Hosp Seidman, Ctr Canc, Case Comprehens Canc Ctr, Cleveland, OH USA

[23] Cleveland Clin, Taussig Canc Inst, Cleveland, OH USA

[24] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

[25] City Hope Comprehens Canc Ctr, Duarte, CA USA

[26] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[27] Washington Univ, Sch Med, St Louis, MO 63130 USA

[28] Dana Farber Brigham & Womens Canc Ctr, Milford, MA USA

[29] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[30] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2017年 / 15卷 / 02期

关键词：

STEM-CELL TRANSPLANTATION; HIGH-DOSE THERAPY; DONOR LYMPHOCYTE INFUSIONS; SINGLE-AGENT CARFILZOMIB; TERM-FOLLOW-UP; BORTEZOMIB PLUS DEXAMETHASONE; INTERNATIONAL STAGING SYSTEM; INTERGROUPE FRANCOPHONE; INDUCTION THERAPY; LENALIDOMIDE MAINTENANCE;

D O I：

10.6004/jnccn.2017.0023

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-related complications include hypercalcemia, renal insufficiency, anemia, and infections. The NCCN Multiple Myeloma Panel members have developed guidelines for the management of patients with various plasma cell dyscrasias, including solitary plasmacytoma, smoldering myeloma, multiple myeloma, systemic light chain amyloidosis, and Waldenstrom's macroglobulinemia. The recommendations specific to the diagnosis and treatment of patients with newly diagnosed MM are discussed in this article.

引用

页码：230 / +

页数：26

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