Stroke Prevention in Nonvalvular Atrial Fibrillation A Stakeholder Perspective

被引：51

作者：

Alkhouli, Mohamad ^{[1
,2
]}

Noseworthy, Peter A. ^{[1
,3
]}

Rihal, Charanjit S. ^{[3
]}

Holmes, David R., Jr. ^{[1
]}

机构：

[1] Mayo Clin, Dept Cardiovasc Dis, Rochester, MN USA

[2] West Virginia Univ, Dept Med, Div Cardiovasc Dis, Morgantown, WV USA

[3] Mayo Clin, Robert D & Patricia E Kern Ctr Sci Hlth Care Deli, Rochester, MN USA

来源：

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2018年 / 71卷 / 24期

关键词：

atrial fibrillation; left atrial appendage; non-vitamin K antagonist oral anticoagulant; oral anticoagulation; risk reduction; stroke; QUALITY-OF-LIFE; ANTAGONIST ORAL ANTICOAGULANTS; RANDOMIZED CONTROLLED-TRIALS; SHARED DECISION-MAKING; VITAMIN-K ANTAGONISTS; APPENDAGE CLOSURE; COST-EFFECTIVENESS; ISCHEMIC-STROKE; NETWORK METAANALYSIS; WARFARIN THERAPY;

D O I：

10.1016/j.jacc.2018.04.013

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ischemic stroke in patients with atrial fibrillation is associated with substantial morbidity and mortality. The growing epidemic of atrial fibrillation worldwide has raised concerns about the dire need for effective stroke prevention systems in these patients. Fortunately, the last decade has witnessed a plethora of data on novel stroke prevention methods in patients with nonvalvular atrial fibrillation. However, optimal selection and effective implementation of these preventative strategies require an integrative approach that takes into account not only the available clinical data but also the perspective of each of the stakeholders involved (patient, physician, and society). The goal of this review was to discuss the contemporary issues surrounding stroke prevention in atrial fibrillation from the perspective of these 3 major stakeholders. (C) 2018 by the American College of Cardiology Foundation.

引用

页码：2790 / 2801

页数：12

共 81 条

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