Triptans and troponin: a case report

被引：9

作者：

Weder, Claudia R. ^{[1
]}

Schneemann, Markus ^{[1
]}

机构：

[1] Univ Zurich Hosp, Dept Internal Med, CH-8091 Zurich, Switzerland

来源：

ORPHANET JOURNAL OF RARE DISEASES | 2009年 / 4卷

关键词：

TRANSMURAL MYOCARDIAL-INFARCTION; ORAL SUMATRIPTAN; MIGRAINE PROPHYLAXIS; 5-HT1B/1D AGONISTS; CARDIAC-ARREST; AMLODIPINE; VASOSPASM;

D O I：

10.1186/1750-1172-4-15

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

This case report describes for the first time acute coronary syndrome in a 67-year old patient after oral intake of naratriptan for migraine. So far in the literature, only sumatriptan, zolmitriptan and frovatriptan have been described to cause acute coronary syndromes. A 67-year old Swiss woman with thoracic pain after intake of 2.5 mg naratriptan presented with T-wave inversions in the ECG and a positive troponin-T at our hospital. Coronary angiography showed normal coronary arteries. Naratriptan-induced coronary vasospasms were thought to have caused the acute coronary syndrome. Triptans should not be prescribed in patients with pre-existing coronary heart disease. However, triptans can also cause acute coronary syndromes in patients without coronary heart disease - as described in our case report. Severe or persistent thoracic pain after intake of triptans should therefore be investigated accordingly.

引用

页数：3

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