Antibiotic efficacy in vivo predicted by in vitro activity

被引:15
作者
Mattie, H [1 ]
机构
[1] Leiden Univ, Med Ctr, Dept Infect Dis, NL-2300 RC Leiden, Netherlands
关键词
in vitro; in vivo; E-max;
D O I
10.1016/S0924-8579(99)00145-4
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A brief overview of arguments found in the literature is presented to apply the E-max concept to experimental studies of antibiotics as well as to their clinical application. It may turn out to be more flexible than schedules based on arbitrary parameters that have the disadvantage that they have to be proven in each individual situation. (C) 2000 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:91 / 98
页数:8
相关论文
共 50 条
[41]   Translation of in vitro cannabinoid 1 receptor agonist activity to in vivo pharmacodynamic endpoints [J].
Jenkinson, Stephen ;
Goody, Susan M. G. ;
Bassyouni, Asser ;
Jones, Rhys ;
Otto-Bruc, Annie ;
Duquennoy, Stephanie ;
DaSilva, Jamie K. ;
Butler, Paul ;
Mead, Andy .
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2020, 104
[42]   IN VITRO AND IN VIVO ANTI-PLASMODIAL ACTIVITY OF ESSENTIAL OILS, INCLUDING HINOKITIOL [J].
Fujisaki, Ryuichi ;
Kamei, Kiyoko ;
Yamamura, Mariko ;
Nishiya, Hajime ;
Inouye, Shigeharu ;
Takahashi, Miki ;
Abe, Shigeru .
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH, 2012, 43 (02) :270-279
[43]   Developmental effects of ketamine on inspiratory hypoglossal nerve activity studied in vivo and in vitro [J].
Berger, Albert J. ;
Sebe, Joy .
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2007, 157 (2-3) :206-214
[44]   Applications and Biological Activity of Nanoparticles of Manganese and Manganese Oxides in In Vitro and In Vivo Models [J].
Sobanska, Zuzanna ;
Roszak, Joanna ;
Kowalczyk, Kornelia ;
Stepnik, Maciej .
NANOMATERIALS, 2021, 11 (05)
[45]   In vitro vs in vivo Pb effects on brain protein kinase C activity [J].
Cremin, JD ;
Smith, DR .
ENVIRONMENTAL RESEARCH, 2002, 90 (03) :191-199
[46]   In vitro and in vivo activity of voriconazole and benznidazole combination on trypanosoma cruzi infection models [J].
Nicolas Gulin, Julian Ernesto ;
Anne Eagleson, Mackenzie ;
Lopez-Munoz, Rodrigo A. ;
Elisa Solana, Maria ;
Altcheh, Jaime ;
Garcia-Bournissen, Facundo .
ACTA TROPICA, 2020, 211
[47]   Immunomodulatory Activity in Vitro and in Vivo of Verbascose from Mung Beans (Phaseolus aureus) [J].
Dai, Zhuqing ;
Su, Di ;
Zhang, Yun ;
Sun, Yi ;
Hu, Bing ;
Ye, Hong ;
Jabbar, Saqib ;
Zeng, Xiaoxiong .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 62 (44) :10727-10735
[48]   An insight investigation to the antiurolithic activity of Trachyspermum ammi using the in vitro and in vivo experiments [J].
Aslam Khan ;
Anwar H. Gilani .
Urolithiasis, 51
[49]   In vitro and in vivo anticancer activity of a novel puerarin nanosuspension against colon cancer, with high efficacy and low toxicity [J].
Wang, Yancai ;
Ma, Yingying ;
Zheng, Ying ;
Song, Ju ;
Yang, Xiao ;
Bi, Chao ;
Zhang, Dianrui ;
Zhang, Qiang .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2013, 441 (1-2) :728-735
[50]   UV Light Killing Efficacy of Fluorescent Protein-Expressing Cancer Cells In Vitro and In Vivo [J].
Kimura, Hiroaki ;
Lee, Claudia ;
Hayashi, Katsuhiro ;
Yamauchi, Kensuke ;
Yamamoto, Norio ;
Tsuchiya, Hiroyuki ;
Tomita, Katsuro ;
Bouvet, Michael ;
Hoffman, Robert M. .
JOURNAL OF CELLULAR BIOCHEMISTRY, 2010, 110 (06) :1439-1446