Palladium-catalyzed ortho-acylation of 2-benzyl-1,2,3-triazoles with aldehydes

被引：19
|
作者：
Tian, Qingshan [1 ]
He, Ping [1 ]
Kuang, Chunxiang [1 ,2 ]
机构：
[1] Tongji Univ, Dept Chem, Shanghai 200092, Peoples R China
[2] Minist Educ, Key Lab Yangtze River Water Environm, Shanghai 200092, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 38期
关键词：
C-H BONDS; DECARBOXYLATIVE ORTHO-ACYLATION; ALPHA-OXOCARBOXYLIC ACIDS; TOLUENE DERIVATIVES; DIRECT ARYLATIONS; BENZOIC-ACIDS; RUTHENIUM; FUNCTIONALIZATION; ACETANILIDES; ACTIVATION;
D O I：
10.1039/c4ob01406e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A palladium-catalyzed ortho-acylation of 2-benzyl-1,2,3-triazoles with aldehydes as an acyl source was developed. A wide variety of ketones containing 1,2,3-triazoles were obtained in good to excellent yields. This methodology provides a convenient access to the acylation of 2-substituted-1,2,3-triazoles.
引用
收藏
页码：7474 / 7477
页数：4
相关论文
共 50 条
  • [1] Palladium-Catalyzed ortho-Acylation of 2-Aryl-1,2,3-triazoles with Toluene Derivatives
    He, Ping
    Tian, Qingshan
    Kuang, Chunxiang
    SYNTHESIS-STUTTGART, 2015, 47 (09): : 1309 - 1316
  • [2] Palladium-catalyzed ortho-C-H alkenylation of 2-benzyl-1,2,3-triazoles
    He, Ping
    Tiana, Qingshan
    Kuang, Chunxiang
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 13 (26) : 7146 - 7148
  • [3] Palladium-Catalyzed Acylation of 2-Aryl-1,2,3-triazoles with Aldehydes
    Wang, Zechao
    Tian, Qinshan
    Yu, Xin
    Kuang, Chunxiang
    ADVANCED SYNTHESIS & CATALYSIS, 2014, 356 (05) : 961 - 966
  • [4] Palladium-catalyzed ortho-acylation of 2-arylbenzoxazoles
    Zhang, Qian
    Li, Chao
    Yang, Fan
    Li, Jingya
    Wu, Yangjie
    TETRAHEDRON, 2013, 69 (01) : 320 - 326
  • [5] Palladium-Catalyzed Ortho-Alkoxylation of 2-Aryl-1,2,3-triazoles
    Shi, Suping
    Kuang, Chunxiang
    JOURNAL OF ORGANIC CHEMISTRY, 2014, 79 (13): : 6105 - 6112
  • [6] Regioselective ortho-Acylation of N-Aryl-1,2,3-triazoles with Alcohols in Water
    Premi, Chanchal
    Patel, Shyam Sunder
    Jain, Nidhi
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 2016 (22) : 3788 - 3795
  • [7] Palladium-Catalyzed Dehydrogenative Direct Arylations of 1,2,3-Triazoles
    Ackermann, Lutz
    Jeyachandran, Rajkumar
    Potukuchi, Harish K.
    Novak, Petr
    Buettner, Lea
    ORGANIC LETTERS, 2010, 12 (09) : 2056 - 2059
  • [8] Palladium-Catalyzed Direct Diarylation of 2-Benzyl-1,2,3-triazole: a Simple Access to 4-Aryl- or 4,5-Diaryl-2-benzyl-1,2,3-triazoles and Phenanthro[9,10-d][1,2,3]triazoles
    Shi, Xinzhe
    Zhang, Jian
    Roisnel, Thierry
    Soule, Jean-Francois
    Doucet, Henri
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 2021 (17) : 2375 - 2382
  • [9] Palladium-Catalyzed C-H Arylation of 1,2,3-Triazoles
    Zhang, Chengwei
    You, Lin
    Chen, Chuo
    MOLECULES, 2016, 21 (10)
  • [10] Palladium-Catalyzed Decarboxylative ortho-Acylation of Benzamides with α-Oxocarboxylic Acids
    Jing, Kun
    Yao, Jia-Ping
    Li, Zhong-Yuan
    Li, Qi-Li
    Lin, Hao-Sheng
    Wang, Guan-Wu
    JOURNAL OF ORGANIC CHEMISTRY, 2017, 82 (23): : 12715 - 12725
12345