Synthesis of Substituted N-[4(5-Methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl]benzamide/benzene Sulfonamides as Anti-Inflammatory and Anti-Cancer Agents

被引:9
作者
Gangapuram, Madhavi [1 ]
Redda, Kinfe K. [1 ]
机构
[1] Florida A&M Univ, Coll Pharm & Pharmaceut Sci, Tallahassee, FL 32307 USA
关键词
N-(SUBSTITUTED BENZOYLAMINO)-5-CARBETHOXYMETHYL-1,2,3,6-TETRAHYDROPYRIDINES; ALZHEIMERS-DISEASE; 1,3,4-OXADIAZOLES; SERIES; DRUGS; TETRAHYDROPYRIDINES; 1,3,4-THIADIAZOLES; AGONIST;
D O I
10.1002/jhet.62
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Fourteen novel substituted N-[4(5-methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl] benzamide/benzene sulfonamides (11a-n) were synthesized in fair to good yields via sodium borohydride reduction of the corresponding substituted N-(benzoylimino)-4-(5-methyl/5-phenyl-1,3,4-oxadiazol-2yl) pyridinium ylide (10a-n) in absolute ethanol.
引用
收藏
页码:309 / 316
页数:8
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