Focus article: report of the NIH task force on research standards for chronic low back pain

被引：54

作者：

Deyo, Richard A. ^{[1
]}

Dworkin, Samuel F. ^{[2
]}

Amtmann, Dagmar ^{[2
]}

Andersson, Gunnar ^{[3
]}

Borenstein, David ^{[4
]}

Carragee, Eugene ^{[5
]}

Carrino, John ^{[6
]}

Chou, Roger ^{[1
]}

Cook, Karon ^{[7
]}

DeLitto, Anthony ^{[8
,9
]}

Goertz, Christine ^{[10
]}

Khalsa, Partap ^{[11
]}

Loeser, John ^{[2
]}

Mackey, Sean ^{[5
]}

Panagis, James ^{[12
]}

Rainville, James ^{[13
]}

Tosteson, Tor ^{[14
]}

Turk, Dennis ^{[2
]}

Von Korff, Michael ^{[15
]}

Weiner, Debra K. ^{[8
,9
]}

机构：

[1] Oregon Hlth & Sci Univ, Portland, OR 97239 USA

[2] Univ Washington, Seattle, WA 98195 USA

[3] Rush Univ, Med Ctr, Chicago, IL 60612 USA

[4] George Washington Univ, Washington, DC USA

[5] Stanford Univ, Stanford, CA 94305 USA

[6] Johns Hopkins Univ, Baltimore, MD USA

[7] Northwestern Univ, Evanston, IL USA

[8] VA Pittsburgh Healthcare Syst, Pittsburgh, PA USA

[9] Univ Pittsburgh, Pittsburgh, PA USA

[10] Palmer Coll Chiropract, Davenport, IA USA

[11] Natl Ctr Complementary & Alternat Med, Bethesda, MD USA

[12] NIAMSD, Bethesda, MD 20892 USA

[13] New England Baptist Hosp, Roxbury Crossing, MA USA

[14] Dartmouth Coll, Hanover, NH USA

[15] Grp Hlth Res Inst, Seattle, WA USA

来源：

EUROPEAN SPINE JOURNAL | 2014年 / 23卷 / 10期

关键词：

Low back pain; Chronic low back pain; Research standards; Minimum dataset; NIH Task Force; DEFINING CHRONIC PAIN; FUNCTION ITEM BANK; QUALITY-OF-LIFE; SCREENING TOOL; START BACK; PRIMARY-CARE; PROGNOSTIC APPROACH; OUTCOME MEASURES; CLINICAL-TRIALS; INTERVENTIONAL THERAPIES;

D O I：

10.1007/s00586-014-3540-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

引用

页码：2028 / 2045

页数：18

共 123 条

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