Aortic valve calcification in chronic kidney disease

被引：96

作者：

Rattazzi, Marcello ^{[1
]}

Bertacco, Elisa ^{[1
]}

Del Vecchio, Antonio ^{[2
]}

Puato, Massimo ^{[1
]}

Faggin, Elisabetta ^{[1
]}

Pauletto, Paolo ^{[1
]}

机构：

[1] Univ Padua, Dept Med, Padua, Italy

[2] Monselice Hosp, Unit Nephrol & Dialysis, Padua, Italy

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 2013年 / 28卷 / 12期

关键词：

aortic stenosis; fetuin-A; matrix-GLA-protein; phosphate; vascular calcification; ALL-CAUSE MORTALITY; STAGE RENAL-DISEASE; GROWTH-FACTOR; 23; MITRAL ANNULAR CALCIFICATION; CONVERTING ENZYME-INHIBITORS; LEFT-VENTRICULAR HYPERTROPHY; KAPPA-B LIGAND; HEMODIALYSIS-PATIENTS; VASCULAR CALCIFICATION; CARDIOVASCULAR MORTALITY;

D O I：

10.1093/ndt/gft310

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

Several clinical studies reported an increased prevalence and accelerated progression of aortic valve calcification among patients with end-stage renal disease when compared with subjects with normal kidney function. Recently, mechanisms of calcific valve degeneration have been further elucidated and many of the pathways involved could be amplified in patients with decreased renal function. In particular, calcium-phosphate balance, MGP metabolism, OPG/RANK/RANKL triad, fetuin-A mineral complexes and FGF-23/Klotho axis have been shown to be impaired among patients with advanced chronic kidney disease and could play a role during vascular/valve calcification. The scope of the present review is to summarize the clinical data and the pathophysiological mechanisms potentially involved in the link between renal function decline and the progression of aortic valve disease.

引用

页码：2968 / 2976

页数：9

共 89 条

[71] Uraemic hyperparathyroidism causes a reversible inflammatory process of aortic valve calcification in rats [J].

Shuvy, Mony ;

Abedat, Suzan ;

Beeri, Ronen ;

Danenberg, Haim D. ;

Planer, David ;

Ben-Dov, Iddo Z. ;

Meir, Karen ;

Sosna, Jacob ;

Lotan, Chaim .

CARDIOVASCULAR RESEARCH, 2008, 79 (03) :492-499

[72] Elevated osteoprotegerin is associated with all-cause mortality in CKD stage 4 and 5 patients in addition to vascular calcification [J].

Sigrist, Mhairi K. ;

Levin, Adeera ;

Er, Lee ;

McIntyre, Chris W. .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2009, 24 (10) :3157-3162

[73]

STRAUMANN E, 1992, BRIT HEART J, V67, P236

[74] Association of Cardiac Valvular Calcifications and C-Reactive Protein With Cardiovascular Mortality in Incident Hemodialysis Patients: A Japanese Cohort Study [J].

Takahashi, Hiroshi ;

Ishii, Hideki ;

Aoyama, Toru ;

Kamoi, Daisuke ;

Kasuga, Hirotake ;

Ito, Yasuhiko ;

Yasuda, Kaoru ;

Tanaka, Miho ;

Yoshikawa, Daiji ;

Maruyama, Shoichi ;

Matsuo, Seiichi ;

Murohara, Toyoaki ;

Yuzawa, Yukio .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2013, 61 (02) :254-261

[75] Early and Late Outcomes of Aortic Valve Replacement in Dialysis Patients [J].

Tanaka, Keisuke ;

Tajima, Kazuyoshi ;

Takami, Yoshiyuki ;

Okada, Noritaka ;

Terazawa, Sachie ;

Usui, Akihiko ;

Ueda, Yuichi .

ANNALS OF THORACIC SURGERY, 2010, 89 (01) :65-+

[76] Heart valve calcifications in patients with end-stage renal disease: Analysis for risk factors [J].

Tarrass, Faissal ;

Benjelloun, Meryem ;

Zamd, Mohamed ;

Medkouri, Ghislaine ;

Hachim, Khadija ;

Benghanem, Mohamed Gharbi ;

Ramdani, Benyounes .

NEPHROLOGY, 2006, 11 (06) :494-496

[77] Relationship between aortic valve sclerosis and left ventricular hypertrophy in chronic haemodialysis patients [J].

Turkmen, Funda ;

Emre, Ayse ;

Ozdemir, Ali ;

Sevinc, Can ;

Erisken, Emre ;

Yesilcimen, Kemal .

INTERNATIONAL UROLOGY AND NEPHROLOGY, 2008, 40 (02) :497-502

[78] Relationship of Fibroblast Growth Factor 23 with Left Ventricle Mass Index and Coronary Calcificaton in Chronic Renal Disease [J].

Unsal, Abdulkadir ;

Budak, Sennur Kose ;

Koc, Yener ;

Basturk, Taner ;

Sakaci, Tamer ;

Ahbap, Elbis ;

Sinangil, Ayse .

KIDNEY & BLOOD PRESSURE RESEARCH, 2012, 36 (01) :55-64

[79]

Ureña P, 1999, NEPHROLOGIE, V20, P217

[80] Guidelines on the management of valvular heart disease (version 2012) [J].

Vahanian, Alec ;

Alfieri, Ottavio ;

Andreotti, Felicita ;

Antunes, Manuel J. ;

Baron-Esquivias, Gonzalo ;

Baumgartner, Helmut ;

Borger, Michael Andrew ;

Carrel, Thierry P. ;

De Bonis, Michele ;

Evangelista, Arturo ;

Falk, Volkmar ;

Iung, Bernard ;

Lancellotti, Patrizio ;

Pierard, Luc ;

Price, Susanna ;

Schaefers, Hans-Joachim ;

Schuler, Gerhard ;

Stepinska, Janina ;

Swedberg, Karl ;

Takkenberg, Johanna ;

Von Oppell, Ulrich Otto ;

Windecker, Stephan ;

Zamorano, Jose Luis ;

Zembala, Marian ;

Bax, Jeroen J. ;

Baumgartner, Helmut ;

Ceconi, Claudio ;

Dean, Veronica ;

Deaton, Christi ;

Fagard, Robert ;

Funck-Brentano, Christian ;

Hasdai, David ;

Hoes, Arno ;

Kirchhof, Paulus ;

Knuuti, Juhani ;

Kolh, Philippe ;

McDonagh, Theresa ;

Moulin, Cyril ;

Popescu, Bogdan A. ;

Reiner, Zeljko ;

Sechtem, Udo ;

Sirnes, Per Anton ;

Tendera, Michal ;

Torbicki, Adam ;

Vahanian, Alec ;

Windecker, Stephan ;

Popescu, Bogdan A. ;

Von Segesser, Ludwig ;

Badano, Luigi P. ;

Bunc, Matjaz .

EUROPEAN HEART JOURNAL, 2012, 33 (19) :2451-2496

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