Catalysis for Total Synthesis: A Personal Account

被引:67
作者
Fuerstner, Alois [1 ]
机构
[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany
关键词
gold; iron; molybdenum; natural product synthesis; ruthenium; CROSS-COUPLING REACTIONS; RING-CLOSING-METATHESIS; N-HETEROCYCLIC CARBENES; ARYL GRIGNARD-REAGENTS; METAL-CARBON BONDS; FORMAL TOTAL-SYNTHESIS; OLEFIN-METATHESIS; GOLD CATALYSIS; ALKYNE METATHESIS; CYCLOISOMERIZATION REACTIONS;
D O I
10.1002/anie.201402719
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Divining rod: Natural product synthesis often serves as a divining rod in our search for new and useful catalytic reactivity. This personal account - written in honor of the Max-Planck-Institut für Kohlenforschung on the occasion of its 100th anniversary - summarizes the major lines of research pursued in the author's laboratory, which show how total synthesis and research into basic organometallic chemistry cross-fertilize each other. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:8587 / 8598
页数:12
相关论文
共 219 条
[1]   Ruthenium carbene complexes with imidazolin-2-ylidene ligands allow the formation of tetrasubstituted cycloalkenes by RCM [J].
Ackermann, L ;
Fürstner, A ;
Weskamp, T ;
Kohl, FJ ;
Herrmann, WA .
TETRAHEDRON LETTERS, 1999, 40 (26) :4787-4790
[2]   Iron(I) in Negishi Cross-Coupling Reactions [J].
Adams, Christopher J. ;
Bedford, Robin B. ;
Carter, Emma ;
Gower, Nicholas J. ;
Haddow, Mairi F. ;
Harvey, Jeremy N. ;
Huwe, Michael ;
Angeles Cartes, M. ;
Mansell, Stephen M. ;
Mendoza, Carla ;
Murphy, Damien M. ;
Neeve, Emily C. ;
Nunn, Joshua .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (25) :10333-10336
[3]  
Alcarazo M., 2010, ANGEW CHEM, V122, P2596
[4]   Steering the Surprisingly Modular π-Acceptor Properties of N-Heterocyclic Carbenes: Implications for Gold Catalysis [J].
Alcarazo, Manuel ;
Stork, Timon ;
Anoop, Anakuthil ;
Thiel, Walter ;
Fuerstner, Alois .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (14) :2542-2546
[5]  
[Anonymous], 2014, ANGEW CHEM, V126, P4907
[6]  
[Anonymous], 2013, ANGEW CHEM, V125, P6379
[7]  
[Anonymous], 2009, Angew. Chem
[8]   Lewis acid-catalyzed hydrostannation of acetylenes. Regio- and stereoselective trans-addition of tributyltin hydride and dibutyltin dihydride [J].
Asao, N ;
Liu, JX ;
Sudoh, T ;
Yamamoto, Y .
JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (14) :4568-4571
[9]   NEW GOLD CARBENE COMPLEXES VIA CARBENE TRANSFER-REACTIONS [J].
AUMANN, R ;
FISCHER, EO .
CHEMISCHE BERICHTE-RECUEIL, 1981, 114 (05) :1853-1857
[10]  
Bedford R.B., 2013, ANGEW CHEM INT EDIT, V125, P1323