QUANTITATIVE ANALYSIS OF TIME DELAYS OF GLUCOSE - INSULIN DYNAMICS USING ARTIFICIAL PANCREAS

被引：5
|
作者：
Rathee, Saloni [1 ]
Nilam [1 ]
机构：
[1] Delhi Technol Univ, Dept Appl Math, Delhi 110042, India
来源：
DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B | 2015年 / 20卷 / 09期
关键词：
Mathematical modeling; diabetes; dynamics; artificial pancreas; insulin sensitivity; simulation; OSCILLATIONS; SYSTEM;
D O I：
10.3934/dcdsb.2015.20.3115
中图分类号：
O29 [应用数学];
学科分类号：
070104 ;
摘要：
Time delay in insulin secretion, its absorption and action is a point of consideration in artificial pancreas as it may prove fatal in the extreme situation. The present mathematical model deals with two time delays out of which one occur in insulin secretion and second in its absorption and action. The model assess the change in glucose - insulin dynamics after the induction of different values of these time delays in their respective range. Also, simulation is performed over the model to quantify the amount of two time delays to avoid diabetic comma, which has not been explored much.
引用
收藏
页码：3115 / 3129
页数：15
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