QUANTITATIVE ANALYSIS OF TIME DELAYS OF GLUCOSE - INSULIN DYNAMICS USING ARTIFICIAL PANCREAS

被引：5
|
作者：
Rathee, Saloni [1 ]
Nilam [1 ]
机构：
[1] Delhi Technol Univ, Dept Appl Math, Delhi 110042, India
来源：
DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B | 2015年 / 20卷 / 09期
关键词：
Mathematical modeling; diabetes; dynamics; artificial pancreas; insulin sensitivity; simulation; OSCILLATIONS; SYSTEM;
D O I：
10.3934/dcdsb.2015.20.3115
中图分类号：
O29 [应用数学];
学科分类号：
070104 ;
摘要：
Time delay in insulin secretion, its absorption and action is a point of consideration in artificial pancreas as it may prove fatal in the extreme situation. The present mathematical model deals with two time delays out of which one occur in insulin secretion and second in its absorption and action. The model assess the change in glucose - insulin dynamics after the induction of different values of these time delays in their respective range. Also, simulation is performed over the model to quantify the amount of two time delays to avoid diabetic comma, which has not been explored much.
引用
收藏
页码：3115 / 3129
页数：15
相关论文
共 50 条
  • [1] Analysis of perioperative glucose metabolism using an artificial pancreas
    Okazaki, Mitsuyoshi
    Hayashi, Hironori
    Gabata, Ryousuke
    Ohbatake, Yoshinao
    Shinbashi, Hiroyuki
    Nakanuma, Shinichi
    Makino, Isamu
    Tajima, Hidehiro
    Takamura, Hiroyuki
    Ohta, Tetsuo
    ARTIFICIAL ORGANS, 2021, 45 (09) : 998 - 1005
  • [2] Unannounced Meals in the Artificial Pancreas: Detection Using Continuous Glucose Monitoring
    Ramkissoon, Charrise M.
    Herrero, Pau
    Bondia, Jorge
    Vehi, Josep
    SENSORS, 2018, 18 (03):
  • [3] Artificial Pancreas: In Silico Study Shows No Need of Meal Announcement and Improved Time in Range of Glucose With Intraperitoneal vs. Subcutaneous Insulin Delivery
    Toffanin, Chiara
    Magni, Lalo
    Cobelli, Claudio
    IEEE TRANSACTIONS ON MEDICAL ROBOTICS AND BIONICS, 2021, 3 (02): : 306 - 314
  • [4] Investigation of the factors which influence insulin sensitivity in septic patients with glucose intolerance: analysis with glucose clamp method by means of artificial pancreas
    M Hoshino
    Y Haraguchi
    M Sakai
    H Saegusa
    Critical Care, 6 (Suppl 1):
  • [5] Real-time insulin bolusing for unannounced meals with artificial pancreas
    Turksoy, Kamuran
    Hajizadeh, Iman
    Samadi, Sediqeh
    Feng, Jianyuan
    Sevil, Mert
    Park, Minsun
    Quinn, Laurie
    Littlejohn, Elizabeth
    Cinar, Ali
    CONTROL ENGINEERING PRACTICE, 2017, 59 : 159 - 164
  • [6] From insulin pump and continuous glucose monitoring to the artificial pancreas
    Apablaza, Pamela
    Soto, Nestor
    Codner, Ethel
    REVISTA MEDICA DE CHILE, 2017, 145 (05) : 630 - 640
  • [7] Continuous Glucose, Insulin and Lifestyle Data Augmentation in Artificial Pancreas Using Adaptive Generative and Discriminative Models
    Kalita, Deepjyoti
    Sharma, Hrishita
    Mirza, Khalid B.
    IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2024, 28 (08) : 4963 - 4974
  • [8] Investigation of insulin clearance in septic patients with glucose intolerance: analysis under strict blood glucose control by means of artificial pancreas
    M Hoshino
    Y Haraguchi
    M Sakai
    K Hayashi
    N Miyayama
    H Saegusa
    H Ohsawa
    Critical Care, 5 (Suppl 1):
  • [9] Influence of insulin clearance to glucose tolerance in acutely ill severe patients: analysis with glucose clamp method by means of artificial pancreas
    M Hoshino
    Y Haraguchi
    M Sakai
    I Mizushima
    Y Morita
    M Kobayashi
    Critical Care, 7 (Suppl 2):
  • [10] Study of Two Time Delays in IVGTT Glucose–Insulin Dynamical System
    Rathee S.
    Nilam
    International Journal of Applied and Computational Mathematics, 2017, 3 (Suppl 1) : 1337 - 1346
12345